• Advances in the Understanding of Etiology (I)
• 30 min
  1. Infection and autoimmunity: a two-way relationship

  • Dr. Ricard Cervera
• 35 min
  2. Autoimmunity and atherosclerosis

  • Prof. Johan Frostegard
• 47 min
  3. Endothelium and autoimmunity

  • Prof. Pier Luigi Meroni
• Advances in the Understanding of Etiology (II)
• 22 min
  4. Prolactin has a pathogenic role in systemic lupus erythematosus

  • Prof. Luis Jara-Quezada
• 44 min
  5. Sjögren's syndrome: current knowledge and future prospects

  • Prof. Athanasios G. Tzioufas
• 51 min
  6. Genetic and environmental triggers of autoimmune thyroid diseases

  • Prof. Yaron Tomer
• Advances in Pathogenesis and Clinical Manifestation
• 38 min
  7. The catastrophic antiphospholipid syndrome and the microangiopathic antiphospholipid syndrome

  • Prof. Ronald Asherson
• 20 min
  8. Pathogenic mechanisms of autoantibodies: circulating and local antibodies that form immune complexes

  • Dr. Luís Eduardo Coelho Andrade
• 34 min
  9. Pathogenic mechanisms of autoantibodies: antibodies to intracellular and membrane-bound antigens

  • Dr. Luís Eduardo Coelho Andrade
• 43 min
  10. What causes primary biliary cholangitis?

  • Dr. M. Eric Gershwin
• 30 min
  11. Capillaroscopy in autoimmune rheumatic diseases

  • Prof. Maurizio Cutolo
• Advances in Diagnostic Methodologies (I)
• 26 min
  12. The past, present & future of ANA testing: history and challenges of ANA

  • Prof. Marvin J. Fritzler
• 33 min
  13. The past, present & future of ANA testing: changing bandwidth and future of ANA

  • Prof. Marvin J. Fritzler
• 36 min
  14. Diagnostic methods in autoimmunity

  • Mr. Steven Binder
• 24 min
  15. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 1

  • Prof. Chaim Putterman
  • Dr. Noa Schwartz
• 28 min
  16. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 2

  • Prof. Chaim Putterman
  • Dr. Noa Schwartz
• 48 min
  17. Novel aspects of systemic sclerosis

  • Prof. Gabriele Valentini
• Advances in Diagnostic Methodologies (II)
• 46 min
  18. An update on the multiple faces of celiac disease

  • Prof. Aaron Lerner
• 23 min
  19. Protective autoantibodies

  • Prof. Elias Toubi
• 32 min
  20. CD44 genetic deletion enhances and CD44 antibody targeting attenuates autoimmune inflammation

  • Prof. David Naor
• 44 min
  21. Rheumatic fever: a model of a post-infectious autoimmune disease

  • Prof. Jorge Kalil
• Treatments of autoimmune diseases
• 38 min
  22. Intravenous immunoglobulins: clinical evidence

  • Prof. Shaye Kivity
• Latest Developments in the Field
• 26 min
  23. Adjuvants and autoimmunity

  • Dr. Eitan Israeli
• 46 min
  24. Antiphospholipid syndrome (APS): from pathogenesis to treatment

  • Prof. Roger Levy
• 24 min
  25. Vitamin D and autoimmunity

  • Dr. Shir Azrielant
• 28 min
  26. Pregnancy in rheumatic diseases

  • Prof. Pier Luigi Meroni
• Archived Lectures *These may not cover the latest advances in the field
• 47 min
  27. Pathogenic mechanisms of autoantibodies

  • Prof. Cees Kallenberg
• 41 min
  28. B lymphocytes on the frontline of autoimmunity

  • Prof. Pierre Youinou
• 42 min
  29. Apoptotic cell clearance deficiency

  • Prof. Martin Herrmann
• 34 min
  30. Auto-antibodies as predictors of autoimmune disease

  • Dr. Nicola Bizzaro
• 46 min
  31. Innate immunity and natural autoantibodies

  • Prof. Luc Mouthon
• 45 min
  32. Accelerated atherosclerosis in autoimmune rheumatic disease

  • Dr. Andrea Doria
• 47 min
  33. Pregnancy in autoimmune rheumatic diseases

  • Prof. Angela Tincani
• 42 min
  34. Pulmonary hypertension in the connective tissue disease pathogenesis, clinical features and therapeutic options in 2006

  • Prof. Ronald Asherson
• 39 min
  35. Use of algorithms for high quality diagnostics and handling of patients with autoimmune rheumatic diseases

  • Dr. Allan Wiik
• 24 min
  36. Immunologic mechanisms in systemic lupus erythematosus

  • Prof. Kok-Yong Fong
• 23 min
  37. Osteoimmunology

  • Prof. João Eurico Fonseca
  • Ms. Joana Caetano-Lopes
• 43 min
  38. ANCA-associated systemic vasculitides

  • Prof. Loic Guillevin
• 23 min
  39. The common origin for diverse autoimmune diseases

  • Prof. Juan-Manuel Anaya
• 76 min
  40. Anti-cytokine therapy in rheumatoid arthritis

  • Prof. Piercarlo Sarzi-Puttini
• 40 min
  41. Sjogren's syndrome: autoimmune epithelitis

  • Prof. Haralampos Moutsopoulos
• 31 min
  42. Vitamin D and autoimmunity

  • Dr. Howard Amital
• 25 min
  43. Intravenous immunoglobulins: myth and reality

  • Prof. Zera Tellier

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Autoantibodies content as a disease "fingerprint"
3. Major topics of this lecture
4. Medical challenges (1)
5. Medical challenges (2)
6. Inflammatory rheumatic disease (IRD) diagnostics
7. Diagnostics/prognostics of IRD
8. Optimal user-defined needs
9. Tests used for diagnosis of a disease
10. Laboratory aspects 2006
11. Laboratory medicine 2006
12. Indicating clinical value of test results (1)
13. Indicating clinical value of test results (2)
14. Sensitive assays
15. Example: anti-dsDNA antibodies determination
16. Screening by indirect immunofluorescence (IIF)
17. My postulate
18. Cellular regions: HEp-2 cells
19. Modern testing platforms: are they better?
20. Autoantigen arrays
21. Addressable laser bead immuno-assay
22. Reading the reactions
23. Limitations of solid phase assays
24. Diagnosis vs. differential diagnosis
25. Criteria-based clinical diagnostics
26. Ideal clinical and laboratory collaboration (1)
27. Ideal clinical and laboratory collaboration (2)
28. Making diagnostics appropriate
29. Achieving early diagnosis of IRD
30. Example of an algorithm
31. Principle of autoimmune test guide
32. Algorithm for clinical utility
33. Autoantibody-associated sub-syndromes of IRDs
34. Autoantibody-associated lupus sub-syndromes
35. ANA in glomerular lesions of SLE patients
36. Production of ANA before SLE onset (1)
37. Production of ANA before SLE onset (2)
38. Production of antiphospholipids before SLE onset
39. Genes and autoantibody production in SLE
40. Infrequent ANAs are important
41. Scleroderma: survival rates
42. Anti-centromere associations: limited scleroderma
43. Anti-Th/To RNP associations: limited scleroderma
44. Anti-Scl-70 associations: diffuse scleroderma
45. Anti-RNA pol I associations: diffuse scleroderma
46. Anti-U3 RNP associations: diffuse scleroderma
47. Anti-U1RNP associations: overlap scleroderma
48. Anti-PM/Scl associations: overlap scleroderma
49. Evidence-based laboratory medicine
50. Ultimate importance: clinical outcome
51. Perspectives: health economics
52. Conclusions (1)
53. Conclusions (2)
54. Conclusions (3)
55. Some references

Topics Covered

• Tests to diagnose autoimmune rheumatic diseases
• Parameters to indicate clinical value of test results
• Tests based on different technologies
• Making diagnostics clinically appropriate
• Algorithms for use in family practice and in rheumatology practice
• Detection of early autoimmune disease
• Value for money has to be based on optimal early diagnostic work-up

Links

Series:

• Autoimmunity

Categories:

• Clinical Practice
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Wiik, A. (2007, October 1). Use of algorithms for high quality diagnostics and handling of patients with autoimmune rheumatic diseases [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 22, 2024, from https://doi.org/10.69645/SUSU6162.
Export Citation (RIS)

Publication History

• Published on October 1, 2007
• Archived on May 31, 2018

Financial Disclosures

• Dr. Allan Wiik has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.