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- Advances in the Understanding of Etiology (I)
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1. Infection and autoimmunity: a two-way relationship
- Dr. Ricard Cervera
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2. Autoimmunity and atherosclerosis
- Prof. Johan Frostegard
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3. Endothelium and autoimmunity
- Prof. Pier Luigi Meroni
- Advances in the Understanding of Etiology (II)
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4. Prolactin has a pathogenic role in systemic lupus erythematosus
- Prof. Luis Jara-Quezada
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5. Sjögren's syndrome: current knowledge and future prospects
- Prof. Athanasios G. Tzioufas
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6. Genetic and environmental triggers of autoimmune thyroid diseases
- Prof. Yaron Tomer
- Advances in Pathogenesis and Clinical Manifestation
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8. Pathogenic mechanisms of autoantibodies: circulating and local antibodies that form immune complexes
- Dr. Luís Eduardo Coelho Andrade
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9. Pathogenic mechanisms of autoantibodies: antibodies to intracellular and membrane-bound antigens
- Dr. Luís Eduardo Coelho Andrade
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10. What causes primary biliary cholangitis?
- Dr. M. Eric Gershwin
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11. Capillaroscopy in autoimmune rheumatic diseases
- Prof. Maurizio Cutolo
- Advances in Diagnostic Methodologies (I)
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12. The past, present & future of ANA testing: history and challenges of ANA
- Prof. Marvin J. Fritzler
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13. The past, present & future of ANA testing: changing bandwidth and future of ANA
- Prof. Marvin J. Fritzler
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14. Diagnostic methods in autoimmunity
- Mr. Steven Binder
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15. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 1
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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16. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 2
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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17. Novel aspects of systemic sclerosis
- Prof. Gabriele Valentini
- Advances in Diagnostic Methodologies (II)
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18. An update on the multiple faces of celiac disease
- Prof. Aaron Lerner
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19. Protective autoantibodies
- Prof. Elias Toubi
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21. Rheumatic fever: a model of a post-infectious autoimmune disease
- Prof. Jorge Kalil
- Treatments of autoimmune diseases
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22. Intravenous immunoglobulins: clinical evidence
- Prof. Shaye Kivity
- Latest Developments in the Field
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23. Adjuvants and autoimmunity
- Dr. Eitan Israeli
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24. Antiphospholipid syndrome (APS): from pathogenesis to treatment
- Prof. Roger Levy
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25. Vitamin D and autoimmunity
- Dr. Shir Azrielant
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26. Pregnancy in rheumatic diseases
- Prof. Pier Luigi Meroni
- Archived Lectures *These may not cover the latest advances in the field
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27. Pathogenic mechanisms of autoantibodies
- Prof. Cees Kallenberg
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28. B lymphocytes on the frontline of autoimmunity
- Prof. Pierre Youinou
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29. Apoptotic cell clearance deficiency
- Prof. Martin Herrmann
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30. Auto-antibodies as predictors of autoimmune disease
- Dr. Nicola Bizzaro
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31. Innate immunity and natural autoantibodies
- Prof. Luc Mouthon
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32. Accelerated atherosclerosis in autoimmune rheumatic disease
- Dr. Andrea Doria
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33. Pregnancy in autoimmune rheumatic diseases
- Prof. Angela Tincani
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36. Immunologic mechanisms in systemic lupus erythematosus
- Prof. Kok-Yong Fong
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37. Osteoimmunology
- Prof. João Eurico Fonseca
- Ms. Joana Caetano-Lopes
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38. ANCA-associated systemic vasculitides
- Prof. Loic Guillevin
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39. The common origin for diverse autoimmune diseases
- Prof. Juan-Manuel Anaya
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40. Anti-cytokine therapy in rheumatoid arthritis
- Prof. Piercarlo Sarzi-Puttini
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41. Sjogren's syndrome: autoimmune epithelitis
- Prof. Haralampos Moutsopoulos
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42. Vitamin D and autoimmunity
- Dr. Howard Amital
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43. Intravenous immunoglobulins: myth and reality
- Prof. Zera Tellier
Printable Handouts
Navigable Slide Index
- Introduction
- Pregnancy and the immune system
- SLE and flares during pregnancy
- Pregnancies and patients studied
- Flare definition applied in pregnancy
- Physician judgement and disease activity index
- Flare definition
- Timing of SLE flares in pregnancy
- Flare frequency by timing of pregnancy
- ECLAM score / estrogen levels during pregnancy
- Can we know flare occurrences in advance ?
- Significant predictors of flares
- Pregnant women with SLE can have flares
- Gestational outcome in SLE
- Impact of lupus activity on obstetric outcome
- Gestational outcome in SLE: example
- Gestational outcome in renal SLE
- Identifying patients with a high risk of baby loss
- Predictors of adverse pregnancy outcome
- Predictors of obstetrical /neonatal complications
- Factors that predict prematurity and preeclampsia
- Autoantibodies that affect pregnancy outcome
- Antiphospholipid (APL) antibody definition
- Antiphospholipid (APL) antibody associations
- Beta-2 glycoprotein I (beta-2GPI)
- Two-hit theory in APS
- Placenta: the target of aPL
- Beta-2GPI binds the trophoblast cell membranes
- Revised classification for APS syndrome
- Antiphospholipid antibodies and autoimmunity
- APS is treatable cause of prgnancy loss
- Obstetrical complications
- Newborns from mothers with primary APS (1)
- Newborns from mothers with primary APS (2)
- Thrombosis in the offspring of APS patients
- Transplacental passage of IgG aPL (1)
- Transplacental passage of IgG aPL (2)
- aPL in 12 month old babies
- The influence on fetal development
- Mental developement and maternal autoAbs (1)
- Mental developement and maternal autoAbs (2)
- Clinical success and open questions
- Register of infants from mothers with APS
- IgG isotope can influence pregnancy
- Ro complex
- Anti-Ro/anti-La and autoimmunity
- Anti Ro/SS-A and gestational outcome
- Neonatal lupus model
- Anti Ro/SS-A and congenital heart block (CHB)
- Proposed mechanism of cardiac damage
- The diagnosis of CHB
- In utero detection of first-degree heart block
- Management of CHB
- Antenatal and postnatal exposure to DEX
- 11 CHB children with/without exposure to DEX
- T-cell evaluation in eight DEX exposed children
- Heteroduplex analysis on TCRBV chains
- Oligoclonal expansions of TCR repertoire
- Alessa - case study
- Second pregnancy - case study
- Acknowledgements and contacts
Topics Covered
- Pregnancy and the immune system
- SLE flares during pregnancy
- Gestational outcome in SLE
- Predictors of obstetrical and neonatal complications in SLE
- Autoantibodies that can affect pregnancy outcome: antiphospholipid antibodies
- Obstetrical complications and newborns outcome in antiphospholipid syndrome
- Autoantibodies that can affect pregnancy outcome: anti-Ro/SS-A antibodies
- Neonatal lupus
- Congenital heart block and in utero exposure to dexamethasone
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Tincani, A. (2007, October 1). Pregnancy in autoimmune rheumatic diseases [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 22, 2024, from https://doi.org/10.69645/OLRV6867.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Angela Tincani has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.