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- Overview
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1. An introduction to autism and the autism spectrum
- Prof. Fred Volkmar
- Diagnosis and Classification
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2. The diagnosis of autism spectrum disorders
- Prof. Fred Volkmar
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4. Rett syndrome: a pediatric neurodevelopmental disorder
- Prof. Richard Van Acker
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5. The broad autism phenotype
- Prof. Noah J. Sasson
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6. PDD-NOS: the "unknown continent"
- Prof. Kenneth Towbin
- Epidemiology
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7. The epidemiology of autism spectrum disorders: history and current estimates
- Prof. Eric Fombonne
- Development and Behavior
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10. Diagnosis and clinical management of autism: implications for young children
- Dr. Kelly K. Powell
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11. The school age child with autism/autism spectrum disorders (ASD)
- Prof. Ann Le Couteur
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12. Autism in adulthood: improving the future
- Prof. Emeritus Patricia Howlin
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13. Restricted and repetitive behaviours
- Prof. Sue Leekam
- Prof. Margot Prior
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14. Autism spectrum disorder: psychiatric comorbidities
- Dr. Gerrit van Schalkwyk
- Assessment
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15. Diagnostic and screening instruments for autism
- Prof. Deborah Fein
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16. Psychological assessment of ASD
- Dr. Meghan Miller
- Interventions
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18. Models of educational intervention for people with ASD
- Prof. Sandra Harris
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19. Applied behavior analysis: conceptual foundations
- Dr. Mark J. Palmieri
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20. Applied behavior analysis: application elements
- Dr. Mark J. Palmieri
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22. Understanding and assessing language and communication in children with ASD
- Dr. Patricia A. Prelock
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23. Psychopharmacology of autism
- Prof. Christopher J. McDougle
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24. Evidence-based practices for children with autism spectrum disorder
- Dr. Brian Reichow
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25. TEACCH autism program: supporting the unique learning differences of autism
- Dr. Laura Grofer Klinger
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26. Medical care for children on the autism spectrum
- Dr. Elizabeth Wiesner
- Neurobiology
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28. Penetrance, pleiotropy, and psychiatry 1
- Dr. Jacob A.S. Vorstman
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29. Penetrance, pleiotropy, and psychiatry 2
- Dr. Jacob A.S. Vorstman
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30. Genetics of autism spectrum disorders
- Dr. Matthew State
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31. Neural signatures of atypical social brain development in autism
- Dr. Kevin Pelphrey
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32. Neurochemical research in autism
- Dr. George Anderson
- Theory
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33. Neurocognitive models of autism
- Prof. Stephen Hooper
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34. Autism theory
- Dr. Nick Chown
- Social Policy
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36. Asperger syndrome and legal issues
- Dr. Marc Woodbury-Smith
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37. Siblings of children with autistic spectrum disorders 1
- Prof. Bryna Siegel
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38. Siblings of children with autistic spectrum disorders 2
- Prof. Bryna Siegel
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39. Different kinds of minds contribute to society
- Prof. Temple Grandin
- Archived Lectures *These may not cover the latest advances in the field
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40. Psychological assessment
- Prof. Sally Ozonoff
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42. Assessing communication in ASD
- Prof. Rhea Paul
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43. Behavior intervention and autism
- Dr. Lynn Kern Koegel
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44. Alternative and controversial treatments
- Dr. Tristram Smith
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45. The DX and classification of ASDs: progress and pitfalls
- Prof. Peter Szatmari
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46. Assessment and diagnosis of autism spectrum disorders in toddlers
- Dr. Kasia Chawarska
- Dr. Celine A. Saulnier
Printable Handouts
Navigable Slide Index
- Introduction
- Neurochemical research in autism
- Acetylcholine GABA and glutamate research
- Endogenous opioids, oxytocin and AVP research
- The dopamine research
- The stress response system in autism
- Neurochemical basal functioning in autism
- Neurochemical acute response in autism
- Circadian urinary excretion of norepinephrine
- Circadian urinary excretion of epinephrine
- Serotonin system alterations in autism
- Serotonin - some background
- Location of serotonergic neurons in the CNS
- Serotonin uptake in the platelet
- Rationale for the study of 5-HT in autism
- Intriguing recent 5-HT findings
- Increased platelet serotonin in autism
- Platelet serotonin in the PDD group
- Increased platelet serotonin
- Platelet serotonin in 5-20 year-old Dutch subjects
- Infant and maternal platelet serotonin heritability
- The platelet in autism
- Peripheral serotonin levels prediction model
- Urinary 5-HIAA excretion in autism (1)
- Urinary 5-HIAA excretion in autism (2)
- Platelet serotonin in autism - future directions
- Neurochemical alterations in autism
- Reduced 5-HT2A receptor expression
- Overview of 5HT-2A findings in autism
- 5-HT2 receptor binding in parents of autists
- 5-HT2A receptor in autism: future directions
- Melatonin in autism
- Control and regulation of melatonin secretion
- Reduced melatonin excretion in autism
- Abnormal melatonin synthesis in autism
- Circadian urinary excretion of melatonin in autism
- Excretion of 6-SM in hyperserotonemic autism
- Melatonin in autism: future directions
- Summary
- Thank you
- Collaborators
- References
Topics Covered
- Overview of neurochemical research in autism
- Acetylcholine
- Glutamate
- GABA
- Endogenous opioids
- Oyxtocin & AVP
- Dopamine
- Stress response systems
- Noradrenergic/sympathetic nervous system
- The adrenomedullary system and the HPA axis
- Serotonin and melatonin
Talk Citation
Anderson, G. (2010, September 29). Neurochemical research in autism [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved March 25, 2025, from https://doi.org/10.69645/XLMZ7535.Export Citation (RIS)
Publication History
- Published on September 29, 2010
Financial Disclosures
- Dr. George Anderson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.