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Printable Handouts
Navigable Slide Index
- Introduction
- A playwright's take on memory
- What is a memory?
- Your memories are in your connections
- The multiple memory systems approach
- Destruction of hippocampus and related areas
- A taxonomy of memory (1)
- The time limited role of the hippocampus
- A taxonomy of memory (2)
- An alternative approach
- The complementary learning systems theory
- The neuro-mechanistic theory
- Complementary learning in the hippocampus (1)
- Complementary learning in the hippocampus (2)
- Supporting neurophysiological evidence
- Long term potentiation in the hippocampus
- Theta phase precession
- Complementary learning and representation
- Neurons response to stimuli in the cortex
- Neurons response to stimuli in the hippocampus
- Inner structures of the hippocampus
- Knockout NMDA receptors in dentate gyrus
- Dentate knockout impairs discrimination learning
- Collaboration of hippocampus and neocortex
- Performance of patients in learning word pairs
- Hippocampus-cortex cooperation in memory
- Recap: the neural basis of memory
Topics Covered
- What is a memory?
- Multiple memory systems approach to the neural basis of memory
- A taxonomy of memory
- The complementary learning systems theory
- The neuro-mechanistic theory: processing and learning in neocortex
- Complementary learning system in the hippocampus
- Neurophysical evidence
- Complementary learning and representation
- Inner structures of the hippocampus
- Knockout NMDA receptors in dentate gyrus
- Collaboration of hippocampus and neocortex
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Talk Citation
McClelland, J. (2020, December 16). Memory and its neural basis [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 26, 2024, from https://doi.org/10.69645/DKKJ2254.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. James McClelland has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Update Available
The speaker addresses developments since the publication of the original talk. We recommend listening to the associated update as well as the lecture.
- Full lecture Duration: 45:07 min
- Update Interview Duration: 17:33 min
A selection of talks on Neurology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is James McClelland and I'm
a professor at Stanford University in the Department of Psychology.
I'd like to welcome you to my lecture on Memory and its Neural Basis.
0:12
Let's start by thinking about the phenomenology of human memory.
The quote you see here from the playwright Harold Pinter comes from
a conversation he had with
a theater critic prior to the opening of a play of his called "Old Times",
in which Pinter portrayed the conversation of a couple who were talking about
the time around when they first met and a person who they both knew at that time.
As the play unfolds,
one comes to see how each of the two characters in the play has constructed a very,
very different set of recollections about these earlier experiences.
It fits in with a perspective psychologists take on memory,
which is to view it as a constructive process;
one that uses shreds of information from
particular past experiences and knits them together perhaps
with shreds from other past experiences and with other bits of
knowledge we have to construct a representation of something.
1:16
This constructive view of memory contrasts with
perhaps the lay person's way of thinking about what a memory is,
like a photograph or a copy,
maybe a reduced description like some notes of a previous experience that we can
stick in a file folder and file away so that later on when we want to remember it,
we essentially retrieve this file folder and open it up and inspect its contents.
On this way of thinking,
the thing that we store and the thing that we then
inspect later are essentially one and the same thing.
But in contemporary neuroscientific theories of memory,
we have a very different view of that matter.