• Archived Lectures *These may not cover the latest advances in the field
• 16 min
  1. Introduction to cytogenetics 3

  • Dr. Sioban SenGupta
• 34 min
  2. Population genetics

  • Dr. Murray P. Cox
• 59 min
  3. Inference on human history through DNA

  • Prof. Guido Barbujani
• 37 min
  4. Human adaptation

  • Prof. Rasmus Nielsen
• 44 min
  5. Accessing and using ENCODE data

  • Prof. Peggy Farnham
• 44 min
  6. Pharmacogenetics

  • Prof. Ann Daly
• 33 min
  7. Genetics in forensics

  • Dr. Angel Carracedo
• 29 min
  8. The development and evolution of human gene therapy

  • Prof. Theodore Friedmann
• 33 min
  9. Next generation sequencing technologies

  • Dr. Krishna Veeramah
• 35 min
  10. Copy number variation

  • Dr. Ömer Gökçümen
• 19 min
  11. Molecular structure of the human genome

  • Prof. Jonathan Wolfe
• 36 min
  12. Genome mapping

  • Dr. Simon Gregory
• 42 min
  13. Mitochondrial DNA, molecular genetics and human mitochondrial diseases

  • Prof. Immo Scheffler
• 26 min
  14. Techniques utilized in molecular genetics

  • Dr. Cecil Lewis
• 31 min
  15. Introduction to mutation and disease

  • Prof. Jonathan Wolfe
• 26 min
  16. Introduction to genetic diseases

  • Prof. Jonathan Wolfe
• 15 min
  17. Introduction to cytogenetics 2

  • Dr. Sioban SenGupta
• 23 min
  18. Introduction to cytogenetics 1

  • Dr. Sioban SenGupta
• 45 min
  19. Genetic association studies

  • Prof. David Balding
• 42 min
  20. The Y-chromosome

  • Prof. Mark Jobling
• 42 min
  21. Quantitative genetics and multifactorial inheritance

  • Dr. Lara Bauman
• 28 min
  22. Historical introduction to human diversity II

  • Prof. Dallas Swallow
• 66 min
  23. Mechanisms of DNA repair by recombination

  • Prof. James Haber
• 26 min
  24. Historical introduction to human diversity I

  • Prof. Dallas Swallow

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. We have many ancestors
3. Patterns in our DNA
4. From the pattern to the process
5. Morphological differences
6. Each group harbours extensive diversity
7. Analyses of morphological traits
8. The problem with morphological traits
9. Estimating variances from sequence comparisons
10. Variation within and between populations
11. Independent studies yield vey similar results
12. What does this mean in practice?
13. Mind the numbers
14. Clustering genotypes or haplotypes
15. Structures inferred from SNPs, haplotypes, CNV
16. The problem with genetic traits
17. Continent specific alleles
18. The association of alleles in long haplotypes
19. Genetic diversity outside Africa
20. How is the human population structured?
21. Models of human evolution
22. A model of isolation by distance
23. Evidence for dispersal from Africa
24. Genetic diversity reflects patterns of migration
25. Human evolution and variation (1)
26. Human evolution and variation (2)
27. Human evolution and variation (3)
28. Linguistic and genetic differences are correlated
29. Serial coalescent simulation and ABC
30. Reconstructing the maternal genealogy (1)
31. Reconstructing the maternal genealogy (2)
32. An example
33. Mutation
34. First DNA sequence of a Neandertal
35. Neandertals not modern Europeans' ancestors (1)
36. Neandertals not modern Europeans' ancestors (2)
37. Why is the human population structured this way?
38. Summary
39. References: patterns
40. References: processes

Topics Covered

• Human population structure
• Racial catalogs based on morphology
• Genetic variation within and between populations
• Genetic clustering of human populations
• Isolation by distance
• A recent demographic expansion from Africa
• Testing evolutionary hypotheses by coalescent simulation
• Ancient DNA

Links

Series:

• Introduction to Human Genetics

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on December 28, 2009
• Archived on September 8, 2024

Financial Disclosures

• Prof. Guido Barbujani has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.