• Basic Concepts
• 19 min
  1. Molecular structure of the human genome

  • Prof. Jonathan Wolfe
• 31 min
  2. Introduction to mutation and disease

  • Prof. Jonathan Wolfe
• 26 min
  3. Introduction to genetic diseases

  • Prof. Jonathan Wolfe
• 26 min
  4. Historical introduction to human diversity I

  • Prof. Dallas Swallow
• 28 min
  5. Historical introduction to human diversity II

  • Prof. Dallas Swallow
• 23 min
  6. Introduction to cytogenetics 1

  • Dr. Sioban SenGupta
• 15 min
  7. Introduction to cytogenetics 2

  • Dr. Sioban SenGupta
• 16 min
  8. Introduction to cytogenetics 3

  • Dr. Sioban SenGupta
• 42 min
  9. The Y-chromosome

  • Prof. Mark Jobling
• 42 min
  10. Mitochondrial DNA, molecular genetics and human mitochondrial diseases

  • Prof. Immo Scheffler
• 66 min
  11. Mechanisms of DNA repair by recombination

  • Prof. James Haber
• 26 min
  12. Techniques utilized in molecular genetics

  • Dr. Cecil Lewis
• 36 min
  13. Genome mapping

  • Dr. Simon Gregory
• 35 min
  14. Copy number variation

  • Dr. Ömer Gökçümen
• Genetics and Disease
• 45 min
  15. Genetic association studies

  • Prof. David Balding
• 42 min
  16. Quantitative genetics and multifactorial inheritance

  • Dr. Lara Bauman
• Human Evolutionary Genetics
• 34 min
  17. Population genetics

  • Dr. Murray P. Cox
• 59 min
  18. Inference on human history through DNA

  • Prof. Guido Barbujani
• 37 min
  19. Human adaptation

  • Prof. Rasmus Nielsen
• Specialized Topics
• 44 min
  20. Accessing and using ENCODE data

  • Prof. Peggy Farnham
• 44 min
  21. Pharmacogenetics

  • Prof. Ann Daly
• 33 min
  22. Genetics in forensics

  • Dr. Angel Carracedo
• 29 min
  23. The development and evolution of human gene therapy

  • Prof. Theodore Friedmann
• 33 min
  24. Next generation sequencing technologies

  • Dr. Krishna Veeramah

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. The inherited nature of diversity in humans
3. Person to person variability
4. Human biochemical genetics
5. Inborn errors of metabolism (1)
6. Alkaptonuria is an inborn error of metabolism
7. Inborn errors of metabolism (2)
8. Phenylketonuria is an inborn error of metabolism
9. Why was there recessive inheritance?
10. Abundant and structural proteins
11. Haemoglobin as an example of abundant protein
12. Sickle cell vs. normal cell
13. Homozygous vs. heterozygous
14. Hb molecular difference shown by electrophoresis
15. Amino acid substitution
16. Polymorphism
17. Blood groups as an example of polymorphism
18. The ABO gene codes for a glycosyltransferase
19. Pharmacogenetics and pharmacogenomics
20. Sensitivity to suxamethonium
21. G6PD deficiency
22. G6PD deficient individuals sensitive to fava beans
23. G6PD activity
24. G6PD distribution - summary
25. G6PD electrophoresis
26. Formal definition of polymorphism

Topics Covered

• The inherited nature of diversity in humans
• Person to person variability
• Human biochemical genetics
• Inborn errors of metabolism
• Alkaptonuria
• Phenylketonuria
• Recessive inheritance
• Abundant and structural proteins
• Sickle cell anaemia
• Pharmacogenetics and pharmacogenomics
• G6PD deficiency

Links

Series:

• Introduction to Human Genetics

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on December 28, 2009
• Archived on September 8, 2024

Financial Disclosures

• Prof. Dallas Swallow has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.