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- Principles in Bacterial Pathogenesis
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1. The molecular basis of bacterial pathogenicity: an overview
- Prof. B. Brett Finlay
- Gram Negative Pathogens
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2. Deciphering shigella invasion of epithelial cells
- Prof. Philippe Sansonetti
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5. Bordetella pertussis
- Prof. Alison Weiss
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6. Salmonellae: molecular basis of infection
- Prof. Samuel Miller
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7. The diversity of Escherichia coli infections
- Prof. Michael Donnenberg
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8. Bacterial activation of epithelial signaling
- Prof. Alice Prince
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9. Human pathogenic Yersinia species
- Prof. James Bliska
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11. Dental pathogens
- Prof. Ann Progulske-Fox
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12. Haemophilus
- Prof. Robert Munson
- Gram Positive Pathogens
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13. The bacterial pathogen Listeria monocytogenes: an amazing multifaceted model
- Prof. Pascale Cossart
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15. Molecular pathogenesis and prevention of Staphylococcus aureus infections
- Prof. Olaf Schneewind
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16. Streptococcus pyogenes disease and molecular pathogenesis
- Prof. P. Patrick Cleary
- Host Responses
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17. Microbial recognition and the immune response
- Dr. Dana Philpott
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18. Enteric pathogens-microbiota-host inter-kingdom chemical interactions
- Prof. Vanessa Sperandio
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19. Toll-like receptor signalling during infection and inflammation
- Prof. Luke O'Neill
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20. The human indigenous microbiota
- Prof. David Relman
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22. Role of neutrophils in acute lung injury and repair
- Prof. Gregory Downey
- Preventatives and Therapeutics
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23. Antibiotics and antibiotic resistance
- Prof. Gerry Wright
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24. Vaccines: a health insurance of the 21st century
- Prof. Rino Rappuoli
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25. Biodefense vaccines
- Prof. James Nataro
- Archived Lectures *These may not cover the latest advances in the field
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26. Vaccines in the modern world
- Prof. Gordon Dougan
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27. Bacterial infection of epithelial signaling
- Prof. Alice Prince
Printable Handouts
Navigable Slide Index
- Introduction
- E. coli can be commensal
- E. coli can cause infections
- How can E. coli cause so many diseases?
- How do E. coli strains differ from one another?
- ExPEC
- UPEC pathogenesis
- UPEC virulence factors
- ExPEC gene discovery techniques
- Sugar coating
- K2 capsule and serum resistance
- ETEC disease
- ETEC pathogenesis
- Chromosomal factors in ETEC pathogenesis
- EPEC disease
- EPEC pathogenesis
- The bundle-forming pilus
- The bfp gene cluster
- A model of the BFP biogenesis machine
- Diversifying selection of bundlin
- Specificity of human Ab response against bundlin
- Attaching and effacing
- The locus of enterocyte effacement
- Intimin
- The translocon of type III secretion system
- EspB damages the brush border in vivo
- The translocated Intimin receptor
- EPEC summary
- EHEC
- EHEC clinical features
- Hemolytic-uremic syndrome (HUS)
- The relationship between EPEC and STEC
- The role of eae in attachment in vivo
- Shiga toxins
- Shiga toxin production
- Do antibiotics increase HUS risk?
- EHEC diagnosis
- EHEC therapy
- EHEC prevention
- EAEC
- EAEC pathogenesis
- EIEC and Shigella
- DAEC
- Summary
- Relationships among pathogenic E. coli
- Acknowledgements
Topics Covered
- How can E. coli cause so many diseases?
- Different E. coli strains
- ExPEC
- UPEC pathogenesis and virulence factors
- ExPEC gene discovery
- ETEC and EPEC disease
- The bundle forming pilus
- BFP biogenesis
- Bundlin
- The locus of enterocyte effacement
- Intimin
- The translocon
- EHEC clinical features
- Shiga toxins
- Do antibiotics increase HUS risk?
- EHEC diagnosis, therapy and prevention
- EAEC pathogenesis
- Relationships among pathogenic E. coli
Links
Series:
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Therapeutic Areas:
Talk Citation
Donnenberg, M. (2009, November 2). The diversity of Escherichia coli infections [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved August 31, 2024, from https://doi.org/10.69645/LZCU2338.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Michael Donnenberg has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.