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- Fundamentals of Evolution and Medicine
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1. Evolutionary medicine
- Prof. Randolph Nesse
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2. Evolution and medicine: from the perspective of an evolutionary biologist
- Prof. Stephen C. Stearns
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3. Developmental plasticity, evolution and the origins of disease
- Dr. Mary Jane West-Eberhard
- Evolutionary Genetics
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4. Genetic variation and human disease
- Dr. David Houle
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6. Ecogenetics, evolutionary biology and human disease
- Prof. Gilbert Omenn
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7. Race in genetics and medicine
- Prof. Jeffrey Long
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8. Health disparities in common complex diseases: a role for genetics?
- Dr. Kathleen Barnes
- Infectious Disease
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10. Evolutionary arms races
- Prof. Mark Pagel
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11. Antibiotic resistance and hospital-acquired infection
- Dr. Carl Bergstrom
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12. Evolution of drug resistance
- Dr. Pleuni Pennings
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13. Evolution of virulence: malaria, a case study
- Prof. Andrew Read
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14. Infection and chronic disease
- Prof. Paul Ewald
- Defenses
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15. Fever and related defenses
- Prof. Matthew Kluger
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16. The evolutionary ecology of immunity
- Prof. Paul Schmid-Hempel
- Novel Environmental Factors
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17. What did humans evolve to eat? evolutionary perspectives on human nutritional health
- Prof. William R. Leonard
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19. The paleolithic lifestyle and prevention of chronic disease
- Prof. S. Boyd Eaton
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22. Diseases of civilization: an evolutionary legacy
- Prof. Alan Weder
- Problems Arising From Constraints and Trade-Offs
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23. Aging and evolutionary medicine
- Prof. Linda Partridge
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24. Human aging and menopause
- Prof. Kristen Hawkes
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25. Why we cook with spices: preventative darwinian medicine
- Prof. Paul Sherman
- Sex and Reproduction
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26. Setting the second stage: the evolution of menopause & post-reproductive life
- Prof. Lynnette Sievert
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27. Evolutionary obstetrics
- Prof. Wenda Trevathan
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28. Sex differences in mortality
- Dr. Daniel Kruger
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29. The endocrinology of human life history transitions
- Prof. Peter Ellison
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30. Genetic conflicts in human pregnancy
- Prof. David Haig
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31. Environmental effects on human reproduction
- Prof. Gillian Bentley
- Cancer
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32. A darwinian eye view of cancer
- Prof. Mel Greaves
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33. Viruses and cancer
- Prof. Robin Weiss
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34. Connecting aging and cancer through the lens of evolution
- Prof. James DeGregori
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35. Evolutionary dynamics in cancer control and cure
- Dr. Bob Gatenby
- Specific Body Systems
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36. Hard tissue biology in human health and evolution: enamel biology
- Prof. Timothy Bromage
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37. Hard tissue biology in human health and evolution: bone biology
- Prof. Timothy Bromage
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38. Hard tissue biology in human health and evolution: craniofacial biology
- Prof. Timothy Bromage
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39. Hard tissue biology in human health and evolution: life history and chronobiology
- Prof. Timothy Bromage
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40. Lung biology and lung disease
- Prof. John S. Torday
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41. The evolutionary web of life
- Prof. John S. Torday
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42. Evolutionary considerations and the endothelium
- Dr. William Aird
- Mental Disorders
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43. Evolutionary psychiatry
- Prof. Randolph Nesse
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44. Evolutionary behavioural genetics and mental disorders
- Dr. Matthew Keller
- Questions and Answers
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45. Audience questions about evolution and medicine
- Prof. Randolph Nesse
- Paediatrics
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46. Evolutionary pediatrics
- Dr. Paul Turke
- Microbiome
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47. Evolution, the microbiome, and human health
- Dr. Joe Alcock
- Archived Lectures *These may not cover the latest advances in the field
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48. The hygiene hypothesis
- Prof. Graham Rook
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49. Mapping motivations: evolutionary health promotion
- Dr. Valerie Curtis
- Dr. Robert Aunger
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50. Evolutionary biology of depression
- Prof. Lewis Wolpert
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51. Evolutionary genetic epidemiology
- Prof. Nicholas Schork
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52. Mental disorders in the light of evolutionary biology
- Prof. Randolph Nesse
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53. Evolution: medicine's missing basic science
- Prof. Randolph Nesse
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54. Environmental effects on human reproduction
- Prof. Gillian Bentley
Printable Handouts
Navigable Slide Index
- Introduction
- "Die Pest" - the Bubonic plague
- A viewpoint
- Darwin's principles
- What do we expect?
- "Mechanism" versus "function"
- "Fitness" has many components!
- Cost of defense (1)
- Cost of defense (2)
- A trade-off
- What kind of costs?
- Cost of using the defense (1)
- Encapsulation - a general response
- Effect of work on immune defense
- Enforcing the immune response
- A survival cost of immunity
- Cost of defense (3)
- Table: cost of using the defense (1)
- Table: cost of using the defense (2)
- Costs of using the defense (2)
- Worse competitor
- Table: cost of evolving the defense "machinery"
- Different interests of the sexes
- Immune defense and sexual selection studies
- Specificity (1)
- Specificity (2)
- Auto-immunity / self-reactivity
- Waypoint (1)
- Strategies: a different view
- Speed and cost of response (1)
- Speed and cost of response (2)
- Limits to removal (1)
- Limits to removal (2)
- Waypoint (2)
- Parasite interference (1)
- Parasite interference (2)
- Examples of immune evasions by parasites
- Strategically robust defenses?
- Principles of strategic robustness
- Summary
- Consequences for medicine
- (Not) the end...
Topics Covered
- Why immune defense matters
- Asking for evolutionary reasons and constraints
- Using immune defenses is very costly for the individual
- The nature of the costs
- Differences among the sexes
- Specific defenses and their impact
- What would be the best defense
- Parasites are interfering
- The consequences for medicine
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Schmid-Hempel, P. (2020, August 16). The evolutionary ecology of immunity [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved January 15, 2025, from https://doi.org/10.69645/GKKN2185.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Paul Schmid-Hempel has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.