• Introduction to Cancer Therapy
• 46 min
  1. Development of a cancer drug

  • Prof. Martin Edelman
• Use of Novel "Targeted" Agents in Combination with Classical Cytotoxic Chemotherapy
• 35 min
  2. Small molecule inhibitors of receptor tyrosine kinases

  • Dr. Daniela Krause
• Innovative Strategies of Clinical Drug Development
• 46 min
  3. Phase II trials

  • Dr. Patricia Tang
• 33 min
  4. Surrogate endpoints of efficacy

  • Prof. Maurie Markman
• Biomarkers in Oncology: Rationale Development and Current Use
• 27 min
  5. Biomarkers in oncology: overview

  • Prof. Joe Duffy
• 55 min
  6. Genetic polymorphism of thiopurine methyltransferase and thiopurine therapy: from molecular genetics to clinical medicine

  • Dr. William Evans
• Archived Lectures *These may not cover the latest advances in the field
• 42 min
  7. Emerging trends in phase II trial design

  • Dr. Patricia Tang
• 36 min
  8. EGFR inhibitors in NSCLC and the role of biomarkers for selection of patients

  • Prof. Fred Hirsch
• 36 min
  9. Therapy in cancer 2008: quo vadis?

  • Dr. Jeffrey Clark
• 34 min
  10. Changing paradigms in anticancer drug development: inhibiting angiogenesis in colorectal cancer

  • Prof. David Kerr
• 32 min
  11. Phase III trials

  • Prof. Martin Edelman
• 43 min
  12. Germline pharmacogenomics as a tool to individualize therapy in breast cancer

  • Dr. David Flockhart
• 33 min
  13. Gene profiling in breast cancer

  • Dr. Enrique Espinosa
• 31 min
  14. UGT1A1 polymorphisms and irinotecan toxicity in colorectal cancer patients

  • Prof. Tae Won Kim
• 28 min
  15. Principles of cancer treatment: surgery, radiotherapy, chemotherapy, immunotherapy

  • Dr. Theodore Yaeger
• 25 min
  16. Understanding cancer trends

  • Prof. Michael Thun
• 54 min
  17. Bevacizumab: the first FDA-approved angiogenesis inhibitor in the treatment of non-small cell lung cancer

  • Dr. Tracey Evans
• 40 min
  18. Phase I study design for non-cytotoxic agents

  • Dr. Wendy Parulekar
• 36 min
  19. Early detection of lung cancer

  • Prof. Stephen Lam
• 60 min
  20. Cytotoxic chemotherapy

  • Dr. Michael Sawyer

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. History of cancer surgery
3. Curative surgery for common cancer sites
4. Surgery - summary
5. History of cancer radiotherapy
6. Basic concepts of radiotherapy
7. Evolution of radiotherapy treatment
8. Modern techniques in radiotherapy
9. Modern radiotherapy - summary
10. Breast radiotherapy
11. History of chemotherapy
12. Biological aspects of chemotherapy
13. Selecting protective intervention in chemotherapy
14. Hormone therapy
15. Novel approaches
16. Anti-angiogenesis
17. History of cancer immunotherapy
18. Immunotherapy - immunosurveillance hypothesis
19. Therapy mechanisms of immunotherapy (1)
20. Therapy mechanisms of immunotherapy (2)
21. Immunotherapy - summary
22. Conclusions (1)
23. Conclusions (2)

Topics Covered

• Historic principles leading to modern cancer treatments
• Specific reviews of surgery, radiotherapy, chemotherapy, hormone therapy and immunotherapy development
• Significant developments in present use
• Modern concepts using combined modality approaches
• Latest technological developments in radiotherapy
• Latest developments and implementation of immunotherapy
• Discussion of near future events and possibilities

Links

Series:

• Cancer Therapy

Categories:

• Cancer
• Clinical Practice

Therapeutic Areas:

• Oncology

Talk Citation

Publication History

• Published on January 6, 2009
• Archived on February 25, 2021

Financial Disclosures

• Dr. Theodore Yaeger has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.