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- Perspective and Pathogenesis
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23 min
1. Expanding frontiers of cerebrovascular disease- Prof. Vladimir Hachinski
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32 min
2. Basic anatomy, physiology and pathophysiology of the cerebral circulation for the physician- Prof. Jean-Claude Baron
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43 min
3. Pathophysiology of cerebral ischemia- Prof. Wolf-Dieter Heiss
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20 min
4. Intracerebral hemorrhages: causes and clinical findings- Prof. Louis Caplan
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40 min
5. Subarachnoid hemorrhage (SAH)- Prof. R. Loch Macdonald
- Diagnosis
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32 min
6. Clinical diagnosis of stroke and subtypes- Prof. Louis Caplan
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30 min
7. The investigation of stroke- Dr. Bart Demaerschalk
- Treatment
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35 min
8. Acute therapy of stroke and reperfusion treatments- Prof. Brian Silver
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39 min
9. Subarachnoid hemorrhage diagnosis and management- Prof. Gary K. Steinberg
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26 min
10. Stroke-induced heart injury- Dr. Luciano A. Sposato
- Rehabilitation
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37 min
11. Stroke rehabilitation: principles of stroke- Prof. Robert Teasell
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27 min
12. Stroke rehabilitation: therapies and treatments- Prof. Robert Teasell
- Prevention
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23 min
13. Lifestyle and nutrition in stroke prevention- Prof. J. David Spence
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40 min
- Special Topics
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54 min
15. Pediatric stroke: cerebrovascular injury in the developing brain- Prof. Adam Kirton
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43 min
16. Stroke in women: epidemiology, risk and prevention- Prof. Cheryl Bushnell
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25 min
17. Transient ischemic attack and cognition- Dr. Jennifer Mandzia
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31 min
18. Vascular cognitive impairment- Prof. Eric E. Smith
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34 min
19. Atrial fibrillation, anticoagulation and vitamins for homocysteine- Prof. J. David Spence
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41 min
20. Stroke in the young adult- Prof. Jeffrey Saver
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16 min
21. Stroke in the young- Dr. Gyan Kumar
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23 min
22. Convergence and joint prevention of stroke and dementia- Prof. Vladimir Hachinski
- Archived Lectures *These may not cover the latest advances in the field
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55 min
23. Vascular cognitive impairment- Dr. John Bowler
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32 min
24. Pediatric stroke- Dr. Gabrielle deVeber
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36 min
25. The deteriorating stroke- Prof. Werner Hacke
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27 min
26. General management- Prof. Bo Norrving
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35 min
27. The treatment of stroke: specific management - thrombolysis plus- Prof. Nils Wahlgren
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42 min
28. Rehabilitation: the chronic phase- Prof. Lalit Kalra
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61 min
29. Prevention: management of risk and protective factors- Prof. Graeme Hankey
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30 min
30. Medical therapy for secondary prevention of ischemic stroke- Prof. Larry Goldstein
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34 min
31. Subarachnoid haemorrhage- Prof. Jan van Gijn
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35 min
32. Controversies in stroke- Prof. Stephen Davies
- Prof. Geoffrey Donnan
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35 min
33. Medical and surgical stroke- Prof. Carlos Kase
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35 min
34. The urgency of stroke prevention after TIA- Prof. S. Claiborne Johnston
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54 min
35. Carotid endarterectomy, angioplasty and stenting- Prof. Martin Brown
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42 min
36. The clinical diagnosis of stroke and stroke subtypes- Prof. Louis Caplan
Printable Handouts
Navigable Slide Index
- Introduction
- Stenosis of the internal carotid artery
- Lecture outline
- Symptoms of carotid stenosis (1)
- A prominent posterior communicating artery
- Symptoms of carotid stenosis (2)
- Superficial borderzone infarction
- Deep borderzone infarction
- Impaired perfusion in deep borderzones
- Other symptoms of carotid artery disease
- Signs of carotid artery disease
- Examination low flow retinopathy
- Cholesterol embolus with retinal infarction
- Indications for carotid endarterectomy
- Stenosis treatment should be evidence based
- Mechanisms of ischaemic stroke
- Analysis of symptomatic carotid surgery trials
- Different methods to measure stenosis
- Analysis results: stenosis 70-99%
- Angiograms of severe stenosis and near occlusion
- Analysis results: near occlusion
- Absolute risk reduction with surgery
- Benefit of carotid endarterectomy
- The effect of surgery by time since last event
- Risk of recurrent stroke prior to endarterectomy
- Carotid endarterectomy for asymptomatic stenosis
- Asymptomatic carotid surgery trial
- Main results of ACST trial
- Carotid territory ischaemic stroke: 5-years risk
- Combined analysis of ACST and ACASA trials
- Benefit from surgery for asymptomatic patients
- HPS study
- Is angioplasty or stenting an alternative?
- Endovascular treatment - alternative to surgery?
- Carotid endarterectomy specimen
- What have we learnt from CAVATAS?
- Inflated angioplasty balloon
- Carotids fit for surgery
- CAVATAS results (1)
- CAVATAS results (2)
- Histology of restenosis after angioplasty
- Conclusions from CAVATAS
- Evolution of endovascular treatment
- Self expanding nitenol stent
- Cerebral protection devices
- Parodi anti-embolism system
- Disadvantages of protection devices
- CAVATAS: timing of strokes after treatment
- Recent prospective case series and registries
- Problems with case series and registry data
- Accuracy of outcome event assessment
- Importance of randomised control trials
- Carotid angioplasty and stenting vs. surgery
- SAPPHIRE trial
- SAPPHIRE trial: intention to treat analysis
- SAPPHIRE trial: results
- SAPPHIRE trial: notable features
- EVA-3S trial: 30 day safety data
- Explanations for the difference in EVA-3S
- CAVATAS: effect of carotid angioplasty/stenting
- SPACE: 30 day safety data
- SPACE: notable features
- Metanalysis of endovascular treatment vs. surgery
- Metanalysis results: stroke or death at 30 days
- Metanalysis results: MI, death, stroke at 30 days
- Metanalysis results: cranial neuropathy
- Metanalysis results: other comparisons
- Numbers of patients included in the metanalysis
- Endovascular vs. surgical treatment: conclusions
- On-going trials of carotid stenting
- Conclusions: treatment of symptomatic stenosis
- Conclusions: endarterectomy after stroke or TIA
- Conclusions: treatment for asymptomatic stenosis
- Conclusions: carotid stenting
- Acknowledgements
Topics Covered
- Symptoms and signs of carotid stenosis
- Imaging features
- Indications for carotid endarterectomy for symptomatic stenosis
- Indications for carotid endarterectomy for asymptomatic stenosis
- Are angioplasty and stenting safe and effective alternatives?
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Brown, M. (2008, October 27). Carotid endarterectomy, angioplasty and stenting [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 30, 2024, from https://doi.org/10.69645/YTVR2010.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Martin Brown has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
