Basics of Pharmacology
This learning journey is designed to provide an introduction to fundamental concepts in pharmacology. It covers topics such as absorption, distribution, metabolism, and excretion. Additionally, it delves into subjects related to drug development and pharmacovigilance.
Table of Contents
- Absorption, Metabolism (Phases 1 and 2), and Excretion
- Limitations of Conventional Dosage Forms and Strategies for Improved Bioavailability
- Routes of Drug Administration and Basic Considerations
- Controlled Release: Advantages and Disadvantages
- Pharmacokinetics: Absorption
- Pharmacokinetics: Distribution and Half-Life
- General Factors Regulating Drug Metabolism
- Drug Development: Three Important Considerations
- What Is Pharmacovigilance and Why Do We Need It?
1. Absorption, Metabolism (Phases 1 and 2), and Excretion
By Dr. Dennis Smith – Pfizer, UK
An excerpt from Introduction to drug metabolism enzymes
2. Limitations of Conventional Dosage Forms and Strategies for Improved Bioavailability
By Prof. Ana Catarina Silva – University Fernando Pessoa and University of Porto, Portugal
An excerpt from Need for drug delivery systems 1
3. Routes of Drug Administration and Basic Considerations
By Prof. Dr. Sven Stegemann – Graz University of Technology, Austria
An excerpt from Routes of drug delivery
4. Controlled Release: Advantages and Disadvantages
By Dr. Michael J. Rathbone – ULTI Pharmaceuticals, New Zealand
An excerpt from The theory and applications of controlled release principles
5. Pharmacokinetics: Absorption
By Dr. Mark Rogge – Takeda Pharmaceuticals, USA
An excerpt from Pharmacokinetics, toxicokinetics and safety margins
6. Pharmacokinetics: Distribution and Half-Life
By Dr. Mark Rogge – Takeda Pharmaceuticals, USA
An excerpt from Pharmacokinetics, toxicokinetics and safety margins
7. General Factors Regulating Drug Metabolism
By Prof. Edward T. Morgan – Department of Pharmacology, Emory University of Medicine, USA
An excerpt from General factors affecting drug metabolism: effect of physiological factors and disease 1
8. Drug Development: Three Important Considerations
By Prof. Michael Kinch – Stony Brook University, USA
An excerpt from Drug development: from discovery to manufacture
9. What Is Pharmacovigilance and Why Do We Need It?
By Dr. Ulrich Hagemann – International Society of Pharmacovigilance, Germany
An excerpt from The multidimensional landscape of pharmacovigilance: introduction and history