Basics of Immunology (part 2)
This learning journey is designed to introduce cells of the immune system such as T lymphocytes, Natural Killer cells, Dendritic cells, B lymphocytes, and chemokines. Disorders of the immune system such as hypersensitivity reactions are also discussed in this journey.
Table of Contents
- The thymus and self-non-self discrimination
- T cell development
- T cell subsets (CD4 and CD8), activation and response
- What are T follicular helper cells?
- Cytotoxic T lymphocytes and their microenvironment
- Understanding Natural Killer Cells
- What are γδ T cells?
- Dendritic cells: nature’s adjuvant
- B cell functions and the B cell receptor
- B cell development
- Chemokines and chemotaxis
- Type I hypersensitivity
- Type II hypersensitivity
- Type III hypersensitivity
- Type IV hypersensitivity
1. The thymus and self-non-self discrimination
By Prof. Georg Holländer – University of Oxford, UK
An excerpt from The thymus and T cell development: a primer
2. T cell development
By Prof. Georg Holländer – University of Oxford, UK
An excerpt from The thymus and T cell development: a primer
3. T cell subsets (CD4 and CD8), activation and response
By Dr. Marc Veldhoen – University of Lisbon, Portugal
An excerpt from Tissue resident memory T cells (TRM)
4. What are T follicular helper cells?
By Prof. Luis Graca – University of Lisbon, Portugal
An excerpt from Tfh and Tfr cells
5. Cytotoxic T lymphocytes and their microenvironment
By Prof. Gillian M. Griffiths – University of Cambridge, UK
An excerpt from Cytotoxic T lymphocytes
6. Understanding Natural Killer Cells
By Dr. Philippa Kennedy – University of Minnesota, USA
An excerpt from Natural killer cells
7. What are γδ T cells?
By Prof. Bruno Silva-Santos – University of Lisbon, Portugal
An excerpt from Gamma delta T-cells
8. Dendritic cells: nature’s adjuvant
By Prof. Paul J. Fairchild – University of Oxford, UK
An excerpt from Dendritic cells: professional antigen presenting cells
9. B cell functions and the B cell receptor
By Prof. Richard Cornall – University of Oxford, UK
An excerpt from B cell biology
10. B cell development
By Prof. Richard Cornall – University of Oxford, UK
An excerpt from B cell biology
11. Chemokines and chemotaxis
By Dr. James E. Pease – Imperial College London, UK
An excerpt from Chemokines
12. Type I hypersensitivity
By Prof. Herman Waldmann – University of Oxford, UK
An excerpt from Hypersensitivity diseases: type 1 hypersensitivity
13. Type II hypersensitivity
By Prof. Sara Marshall – Wellcome Trust, UK
An excerpt from Hypersensitivity diseases: type II-IV hypersensitivity
14. Type III hypersensitivity
By Prof. Sara Marshall – Wellcome Trust, UK
An excerpt from Hypersensitivity diseases: type II-IV hypersensitivity
15. Type IV hypersensitivity
By Prof. Sara Marshall – Wellcome Trust, UK
An excerpt from Hypersensitivity diseases: type II-IV hypersensitivity