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Basics of Immunology (part 2)

This learning journey is designed to introduce cells of the immune system such as T lymphocytes, Natural Killer cells, Dendritic cells, B lymphocytes, and chemokines. Disorders of the immune system such as hypersensitivity reactions are also discussed in this journey.

Table of Contents

  1. The thymus and self-non-self discrimination
  2. T cell development
  3. T cell subsets (CD4 and CD8), activation and response
  4. What are T follicular helper cells?
  5. Cytotoxic T lymphocytes and their microenvironment
  6. Understanding Natural Killer Cells
  7. What are γδ T cells?
  8. Dendritic cells: nature’s adjuvant
  9. B cell functions and the B cell receptor
  10. B cell development
  11. Chemokines and chemotaxis
  12. Type I hypersensitivity
  13. Type II hypersensitivity
  14. Type III hypersensitivity
  15. Type IV hypersensitivity

1. The thymus and self-non-self discrimination

By Prof. Georg Holländer – University of Oxford, UK

An excerpt from The thymus and T cell development: a primer

  • Play The thymus and self-non-self discrimination

2. T cell development

By Prof. Georg Holländer – University of Oxford, UK

An excerpt from The thymus and T cell development: a primer

  • Play T cell development

3. T cell subsets (CD4 and CD8), activation and response

By Dr. Marc Veldhoen – University of Lisbon, Portugal

An excerpt from Tissue resident memory T cells (TRM)

  • Play T cell subsets (CD4 and CD8), activation and response

4. What are T follicular helper cells?

By Prof. Luis Graca – University of Lisbon, Portugal

An excerpt from Tfh and Tfr cells

  • Play What are T follicular helper cells?

5. Cytotoxic T lymphocytes and their microenvironment

By Prof. Gillian M. Griffiths – University of Cambridge, UK

An excerpt from Cytotoxic T lymphocytes

  • Play Cytotoxic T lymphocytes and their microenvironment

6. Understanding Natural Killer Cells

By Dr. Philippa Kennedy – University of Minnesota, USA

An excerpt from Natural killer cells

  • Play Understanding Natural Killer Cells

7. What are γδ T cells?

By Prof. Bruno Silva-Santos – University of Lisbon, Portugal

An excerpt from Gamma delta T-cells

  • Play What are γδ T cells?

8. Dendritic cells: nature’s adjuvant

By Prof. Paul J. Fairchild – University of Oxford, UK

An excerpt from Dendritic cells: professional antigen presenting cells

  • Play Dendritic cells: nature’s adjuvant

9. B cell functions and the B cell receptor

By Prof. Richard Cornall – University of Oxford, UK

An excerpt from B cell biology

  • Play B cell functions and the B cell receptor

10. B cell development

By Prof. Richard Cornall – University of Oxford, UK

An excerpt from B cell biology

  • Play B cell development

11. Chemokines and chemotaxis

By Dr. James E. Pease – Imperial College London, UK

An excerpt from Chemokines

  • Play Chemokines and chemotaxis

12. Type I hypersensitivity

By Prof. Herman Waldmann – University of Oxford, UK

An excerpt from Hypersensitivity diseases: type 1 hypersensitivity

  • Play Type I hypersensitivity

13. Type II hypersensitivity

By Prof. Sara Marshall – Wellcome Trust, UK

An excerpt from Hypersensitivity diseases: type II-IV hypersensitivity

  • Play Type II hypersensitivity

14. Type III hypersensitivity

By Prof. Sara Marshall – Wellcome Trust, UK

An excerpt from Hypersensitivity diseases: type II-IV hypersensitivity

  • Play Type III hypersensitivity

15. Type IV hypersensitivity

By Prof. Sara Marshall – Wellcome Trust, UK

An excerpt from Hypersensitivity diseases: type II-IV hypersensitivity

  • Play Type IV hypersensitivity