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Printable Handouts
Navigable Slide Index
- Introduction
- Contents - cancer basics
- History of cancer timeline
- What’s in a name?
- What causes cancer?
- World cancer statistics
- Prevention
- A series of unfortunate events
- Fearon-Vogelstein model of Carcinogenesis
- Cancer development
- Staging (example: colorectal cancer)
- Staging (diagram)
- Diagnosis: problem
- Diagnosis - symptoms
- Contents - treatment options
- Treating cancer
- Adjuvant versus neo-adjuvant
- Not to be confused with adjunct therapy
- Surgery - history
- Surgery - uses in treating cancer
- Surgery - new techniques
- Radiation - history
- Radiation - uses in treating cancer
- Chemotherapy - history
- Chemotherapy - nitrogen mustard therapy
- Chemotherapy - types of chemotherapy
- Chemotherapy - types of chemotherapy (cont.)
- Log-kill hypothesis
- Chemotherapy - uses in treating cancer
- Hormone therapy - history
- Hormone therapy - uses in treating cancer
- Targeted therapy - uses in treating cancer
- Targeted therapy requires a companion diagnostic
- Suggested guidelines for NSCLC diagnosis
- Contents - treatment resistance
- Many factors influence treatment response
- The tumour genome can be quite different
- The tumour genome is different: karyotype
- Avoiding resistance
- Contents - treatment side effects
- Many side effects
- Reducing side effects
- Contents - palliative care
- What is palliative care?
- Bow tie model of 21st century palliative care
- Treatment options
- Palliative care
- Thank you
Topics Covered
- Cancer basics
- Staging
- Treating cancer
- Surgery
- Radiation
- Chemotherapy
- Log-Kill Hypothesis
- Hormone therapy
- Targeted therapy
- A companion diagnostic
- Treatment resistance
- The tumour genome
- Reducing side effects
- Palliative care
Links
Series:
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Therapeutic Areas:
Talk Citation
Marsh, S. (2018, June 27). Cancer treatment paradigms [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/HXGB8804.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Sharon Marsh has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Other Talks in the Series: Cancer Therapies in the Personalized Medicine Era
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, this is Sharon Marsh and the topic of
this session will be Cancer Treatment Paradigms.
0:09
During this session, we will cover cancer basics,
the different treatment options available including surgery, radiation,
and chemotherapy, hormone therapy,
treatment resistance, treatment side effects,
and an introduction to palliative care.
First, we will overview some of the basics of cancer.
0:30
Cancer is not a modern day phenomenon.
The earliest description of cancer dates back to 3000 BC with
the documentation of different types of breast tumors and ulcers.
Signs of cancer have also been found on the bones of mummies from ancient Egypt
and Peru also dating as far back as 3000 BC.
0:52
The origins of the terminologies around cancer are more recent.
The original word cancer is credited to the Greek physician
Hippocrates who is considered the Father of Medicine.
Hippocrates used the term carcinos and
carcinoma to describe both non-ulcer forming and ulcer-forming tumors.
These words refer to crab in Greek and it was most likely that the word carcinos and
carcinoma were applied to the disease because
the finger-like spreading projections from a cancer called to mind the shape of the crab.
This led to the rewording of the word carcinoma and carcino to cancer,
which is the Latin word for crab later by the Roman physician Celsus.
A couple of centuries after that Galen,
a Greek physician first used the word oncos
which is Greek for swelling to describe tumors.
Although the crab analogy of Hippocrates and
Celsus is still used to describe malignant tumors,
Galen's term is now used as part of the name for cancer specialists, oncologists.