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Navigable Slide Index

1. Introduction
2. The cell cycle consists of four distinct phases
3. The four phases of cell cycle
4. Cell cycle regulation
5. Two processes must alternate in cell division
6. Cell cycle machinery
7. Cell cycle checkpoints
8. The cell cycle engine
9. The role of cyclins and CDKs in cell cycle
10. Regulation of cyclin D-CKD activity
11. The regulation of cell cycle progression
12. Other roles of CDKs and cyclins (1)
13. Other roles of CDKs and cyclins (2)
14. Cell cycle and pRb family proteins
15. Interaction of pRb and E2F transcription factors
16. What is the nature of this interaction?
17. Cell cycle control pathways
18. The pRb and p53 pathways
19. Conclusions
20. Thank you

Topics Covered

• The cell cycle is a complex system which is highly regulated in a temporal manner, via checkpoints and positive and negative feedback loops
• Two processes must alternate during eukaryotic cell division: S-phase and M-phase entry
• Cell cycle checkpoints
• The cell cycle engine
• Cyclin D-CDK activity
• Not all CDKs and cyclins are involved in the regulation of cell cycle
• Cell cycle and pRb family proteins
• Cell cycle control pathways

Links

Series:

• The Cell Division Cycle

Categories:

• Cell Biology

Talk Citation

Giordano, A. (2009, April 30). Cell cycle: a complex network of signals regulating cell proliferation [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved June 1, 2025, from https://doi.org/10.69645/OYVA8686.
Export Citation (RIS)

Publication History

• Published on April 30, 2009
• Archived on May 28, 2025

Financial Disclosures

• Prof. Antonio Giordano has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.