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1. Introduction
2. The interest in yeasts and fungal prions
3. Yeast and fungal prions: a help or a hindrance?
4. Yeast and fungal prions
5. Comparison of prion domains
6. [PSI+] helps resist stress
7. Phenotypic effects of [PSI+] (1)
8. Phenotypic effects of [PSI+] (2)
9. Are yeast prions a help or a hindrance?
10. Infectious entities of yeast
11. Prions in wild Saccharomyces strains
12. Heterokaryon incompatibility requires [Het-s] prion
13. Comment on Het-s
14. [Het-s] serves as a 'meiotic drive' system (1)
15. The meiotic drive phenomenon
16. [Het-s] serves as a 'meiotic drive' system (2)
17. Some "prion domains" cannot be prions
18. Ure2 from various yeasts
19. "Prion domains" that cannot be prions
20. "Prion domains" have non-prion functions
21. Ure2p prion domain required for nitrogen regulation
22. Ure2p turnover: the prion domain sabilizes Ure2p
23. Sup35 prion domain has a non-prion function
24. Rapid evolution of prion domains
25. PrP polymorphism protects from CJD
26. Prion domain variation in Saccharomyces species
27. Sup35 prion domain variation and prion infection
28. Summary
29. Acknowledgements
30. References

Topics Covered

• [URE3] and [PSI+] not found in wild strains indicating they are harmful
• [Het-s] may benefit its host or may result from "meiotic drive"
• Some "prion domains" cannot be prions
• "Prion domains" have non-prion functions
• Rapid evolution of prion domains may protect against infection

Links

Series:

• Prions and Amyloids

Categories:

• Biochemistry
• Cell Biology

Talk Citation

Wickner, R. (2008, September 4). Yeast and fungal prions: a help or a hindrance? [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/IHII4968.
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Publication History

• Published on September 4, 2008
• Archived on February 25, 2021

Financial Disclosures

• Prof. Reed Wickner has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.