- Gene-environment interaction in the development of human traits, including disease
- Conceptual and analytical challenges
- Joint analysis of data on both genetic and environmental factors from epidemiologic studies as a way to increase power to detect a polymorphism (or an exposure) that is associated with disease risk
- Study designs
- Statistical modeling issues in the analysis of data
- Sample size and power calculations for a range of designs
- Specification of parameters
- Ordinal coding
- Hierarchical models
- The analysis of highdimensional "pathway" data (multiple related genes and environmental exposures)
Kraft, P. and Spiegelman, D. (2007, October 1). Statistical issues in epidemiological studies of gene-environment interaction [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks
. Retrieved March 22, 2023, from https://hstalks.com/bs/79/
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Published on October 1, 2007
- Dr. Peter Kraft has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
- Prof. Donna Spiegelman has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.