We noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
Printable Handouts
Navigable Slide Index
- Introduction
- Composition of the eubacterial ribosome
- Principle of translation
- Elongation of the polypeptide chain
- Role of elongation factors EF-G and EF-Tu
- The four phases of translation
- Initiation - sequence of events
- Visualization of ribozome and translation process
- Cryo-electron microscopy of single molecules
- Transfer RNA - tRNA
- Lock and key fit
- The 70S ribosome
- mRNA , tRNA and polypeptide interactions
- The path of tRNA
- The path of mRNA
- Elongation factors and molecular mimicry
- Implications of structural mimicry
- Elongation cycle
- Elongation cycle of protein biosynthesis
- Highly conserved features in ribosomes
- Tree diagram - philogeny of ribosomal RNA
Topics Covered
- Composition of the ribosome
- Principle of translation
- The four phases of translation
- Structure and function of small and large ribosomal subunits
- Role of elongation factors
- The paths of messenger RNA, transfer RNA and the nascent polypeptide
- Elongation cycle and binding positions of elongation factors
- Decoding, peptidyl transfer and translocation
- Phylogenetic conservation of ribosomal architecture
Talk Citation
Frank, J. (2007, October 1). The principle of translation [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 6, 2024, from https://doi.org/10.69645/LCGR8243.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Joachim Frank has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.