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Hello, everyone. My name is Dr. Sarah Fouch. Welcome to this short recording where we will be considering the clinical conditions associated with Streptococcus pneumoniae and the virulence factors that this organism can produce in order to make it a successful pathogen.
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This is a gram positive coccus and it has an oval shape. Streptococci require quite complex growth requirements within their media and blood is a really good example. Streptococci can grow nicely on blood agar. The reason for this is because streptococci are catalase negative. They need to utilise the catalase from the blood in order to break down the toxic hydrogen peroxide into water and oxygen. When we visualise streptococci and Streptococcus pneumoniae colonies, they can either have capsulated colonies or non-capsulated colonies. When they are capsulated, they are usually large and very mucoid. Sometimes you can take the lid off of an agar plate and they are so mucoid, they almost drip into the lid. In comparison, the non-capsulated forms look very small and flat. They almost have a draughtsman piece appearance. I'm talking about the board game, draughts, here where you have the piece that has a little dip in the middle, and we'll discuss why that's the case now.

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