• Epidemiology
• 37 min
  1. Assessment of obesity and classification of patients: historical perspectives and current practice

  • Prof. George Bray
• 40 min
  2. Epidemiology of obesity

  • Prof. Jacob Seidell
• Etiology and Causes
• 59 min
  3. Metabolic, adipose tissue and muscle predictors of obesity

  • Prof. Ian Macdonald
• 41 min
  4. Neural control of food intake and energy balance

  • Prof. Hans-Rudolf Berthoud
• 64 min
  5. Understanding obesity: genes and environment in the determination of body weight

  • Prof. Rudy Leibel
• 47 min
  6. Dietary determinants of obesity

  • Prof. Arne Astrup
• 42 min
  7. Physical inactivity as a determinant of obesity

  • Prof. Wim Saris
• 42 min
  8. Environmental causes of obesity: sociocultural, built environment and economic factors

  • Prof. Shiriki Kumanyika
• 29 min
  9. The developmental origins of obesity

  • Prof. David Barker
• Consequences of Obesity
• 46 min
  10. Obesity, dyslipoproteinemia and inflammation

  • Prof. Robert Eckel
• 23 min
  11. Pathophysiology and management of obesity related hypertension

  • Prof. Arya Sharma
• 22 min
  12. Disorders of overeating

  • Prof. Albert Stunkard
• 20 min
  13. Obesity, weight loss and health-related quality of life

  • Prof. Aila Rissanen
  • Dr. Jarmo Kaukua
• Treatment Options
• 44 min
  14. Lifestyle modification for weight control

  • Prof. Thomas Wadden
• 34 min
  15. Bariatric / obesity surgery

  • Prof. Henry Buchwald
• 48 min
  16. Can obesity be prevented in the current obesogenic environment?

  • Prof. Boyd Swinburn
• 28 min
  17. Pharmacotherapy for obesity: why it is needed

  • Prof. Joe Proietto
• 35 min
  18. Pharmacotherapy for obesity: hunger suppressors

  • Prof. Joe Proietto
• Latest Developments in the Field
• 60 min
  19. Body composition

  • Dr. Steven Heymsfield
• 56 min
  20. Adipose tissue metabolism and obesity

  • Dr. Max Lafontan
• 25 min
  21. Obesity, present and future therapies

  • Prof. Sir Stephen Bloom
• 42 min
  22. Energy expenditure in the lean and obese

  • Prof. Dale Schoeller
• 33 min
  23. Obesity and adiponectin

  • Prof. Philipp Scherer
• 44 min
  24. Ectopic fat: causes, consequences and treatment

  • Prof. Steven Smith
• 47 min
  25. Adipose-immune interactions in obesity

  • Dr. Vishwa Dixit
• 39 min
  26. Health benefits of intentional weight loss

  • Prof. Xavier Pi-Sunyer
• 39 min
  27. Childhood obesity: implications for current and future health

  • Prof. Peter T. Katzmarzyk
• 46 min
  28. The clinical assessment and management of child and adolescent obesity

  • Prof. Louise Baur
• Archived Lectures - These lectures may not cover the latest advances in the field
• 41 min
  29. Gastrointestinal peptides and food intake regulation

  • Prof. Sir Stephen Bloom
• 48 min
  30. Obesity and mortality: questions and controversy

  • Prof. David Allison
• 37 min
  31. Obesity, diabetes and the cluster of the metabolic syndrome

  • Prof. Peter Wilson
• 44 min
  32. New standards in weight management: recent and future drugs for the treatment of obesity

  • Prof. Luc Van Gaal
• 46 min
  33. Health economics of obesity: new insights

  • Dr. Anne Wolf
• 34 min
  34. Bariatric surgery: techniques and mechanisms of action

  • Prof. Walter Pories
• 39 min
  35. Childhood obesity: implications for future health

  • Prof. Peter T. Katzmarzyk
• 14 min
  36. Pharmacotherapy for obesity 1 - the need for pharmacotherapy in weight management

  • Prof. Joe Proietto
• 46 min
  37. Pharmacotherapy for obesity 2 - pharmacological agents in current use & under development

  • Prof. Joe Proietto

Printable Handouts

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Navigable Slide Index

1. Introduction
2. Lipid and lipoprotein metabolism
3. HDL metabolism
4. Obesity,dyslipidemia,inflammation and ASCVD
5. Obesity lipid/lipoprotein abnormalities
6. The consequence of increase in total cholesterol
7. And It's just not fasting TG
8. Mechanisms of hepatic fatty acid to triglyceride
9. Fatty acid metabolism
10. Regulation of lipolysis
11. The antilipolytic effect of insulin
12. Response of FFA to insulin/glucose
13. Insulin inhibition of FFA turnover
14. Insulin action in the liver
15. Is there an effect of CHO independent of insulin?
16. Effect of SRIF on FFA
17. Effect of SRIF on plasma glucose and insulin
18. Effect of SRIF on hypertriglyceridemia
19. Carbohydrate responsive elements
20. SREBP-1c dependent genes in the liver
21. ChREBP and SREBP-1c and hepatic lipogenesis
22. Plasma VLDL-TG in obese and lean men/women
23. VLDL TG kinetics in lean and obese men/women
24. Plasma VLDL-TG kinetics in men/women
25. VLDL TG clearance in lean and obese men/women
26. Adipose tissue LPL responsiveness to insulin
27. Patterns of body fat distribution
28. Visceral adiposity: the critical adipose depot
29. Visceral vs subcutaneous adipose tissue
30. Banting lecture 1998
31. The clustering of risk factors for ASCVD (2)
32. The reduction of HDL cholesterol in obese patients
33. Age-adjusted prevalence of HDL cholesterol
34. Pathogenesis of decreased HDL cholesterol
35. A reason for reductions in HDL cholesterol
36. HDL cholesterol and plasma TG
37. Plasma levels of HDL particles in the MetS
38. Production of HDL particles in the MetS
39. Clearance of HDL particles in the MetS
40. Pathogenesis of increased atherosclerosis
41. The impact of cytokines on obesity and ASCVD
42. Inflammatory markers and insulin resistance
43. Elevated CRP levels in obese adults
44. CRP in overweight and obese men and women
45. Inflammation and obesity
46. Obesity is associated with cytokine burden
47. CRP and body composition
48. Visceral adipose tissue/plasma CRP/oxidized LDL
49. Changes in metabolic syndrome components
50. BMI and CRP in adolescents
51. Weight reduction modifies dyslipidemia
52. Timing of lipid assessment is important
53. Impact of weight reduction on lipids/lipoproteins(1)
54. Impact of weight reduction on lipids/lipoproteins(2)
55. Impact of weight reduction on plasma triglycerides
56. The mechanisms for the reduction in TG in obese
57. Molar ratio of VLDL TG/Apo B-100
58. Relative change in VLDL Apo B-100 secretion
59. VLDL TG secretion: effect of weight reduction
60. Impact of weight reduction on HDL cholesterol
61. HDL cholesterol,weight reduction and stabilization
62. Impact of weight reduction on HDL2 /HDL3
63. A diet restricted in total fat lowers HDL and LDL
64. Impact of weight reduction on LDL cholesterol
65. Change in CRP after 15% weight loss
66. Effect of weight reduction on insulin sensitivity
67. Effect of weight reduction on plasma hs-CRP
68. Effect of weight reduction on interleukin-18 levels
69. Gastric bypass and cytokines at 14 Mo
70. Summary

Topics Covered

• Normal lipid and lipoprotein physiology
• Abnormalities of lipid and lipoprotein physiology in obesity and related mechanisms
• Inflammation and obesity
• The benefit of weight reduction to favorably modify plasma lipids, lipoproteins and the inflammatory burden in obese patients

Links

Series:

• Obesity

Categories:

• Clinical Practice
• Metabolism & Nutrition

Therapeutic Areas:

• Cardiovascular & Metabolic

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Robert Eckel has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.