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Artificial blood: a review of its history, approaches, and future aspects

Published on May 30, 2024   26 min

A selection of talks on Pharmaceutical Sciences

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0:00
The title of this talk is Artificial Blood. By way of introduction, my name is Dr. Mark T. Friedman, Medical Director of the Transfusion Service and Associate Professor of Pathology at NYU Langone Health, Grossman NYU Long Island School of Medicine in Long Island, New York.
0:20
What is blood? Blood is a complex body fluid that is composed of four main constituents. Red blood cells, which we also call erythrocytes. White blood cells or leukocytes. These consist of the granulocytes, the lymphocytes and the monocytes. Platelets, also known as thrombocytes. Plasma, which is the liquid portion of the blood.
0:48
What are the functions of blood? Blood has many functions. It transports oxygen, carbon dioxide, nutrients, hormones and waste products. It regulates body temperature. It regulates fluid, electrolyte, and acid-base balances that's pH balances. It functions in coagulation to halt bleeding and fibrinolysis, that is clot breakdown after hemostasis, and it acts in inflammatory and immune functions to fight infections.
1:22
What is artificial blood, which is the title of this talk after all. Essentially, artificial blood or blood substitutes are synthetic oxygen carriers that are designed to increase tissue oxygenation. Therefore, they do not replace all functions of blood. They are more correctly termed oxygen therapeutic agents. That is because again, they do not replace all the functions of the blood, only the tissue oxygenation component.

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Artificial blood: a review of its history, approaches, and future aspects

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