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Printable Handouts
Navigable Slide Index
- Introduction
- Overview
- The single case controlled observations history
- A long history with influential applications (1)
- A long history with influential applications (2)
- A long history with a growing impact
- N-of-1 RCT definition
- The funnel approach to measurement (1)
- The funnel approach to measurement (2)
- The randomized experimental approach
- Two types of designs
- Phase design
- Alternation design
- Two types of replication
- Simultaneous replication design
- Sequential replication design
- How to randomize and analyze?
- Random assignment in phase designs
- Graphic demonstration of random assignment
- Phase design: numerical example (1)
- Phase design: numerical example (2)
- Random assignment in alternation designs (1)
- Random assignment in alternation designs (2)
- Alternation design: numerical example
- Simultaneous replication design (1)
- Simultaneous replication design (2)
- Sequential replication design (1)
- Sequential replication design (2)
- Validity of N-of-1 RCTs
- External validity of N-of-1 RCTs
- Conclusion
- References (1)
- References (2)
- References (3)
- References (4)
Topics Covered
- History and impact of N-of-1 RCTs
- Distinguishing N-of-1 RCTs: case studies and time series research
- The funnel approach to measurement
- The randomized experimental approach
- Types of N-of-1 designs and replications
- How to randomize and analyze
- Validity of N-of- 1 RCTs
Links
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Talk Citation
Onghena, P. (2007, October 1). N-of-1 randomized clinical trials [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 23, 2024, from https://doi.org/10.69645/MNOD3451.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Patrick Onghena has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.