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- Design
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34 min
1. An introduction to randomization for clinical trials 1- Prof. William Rosenberger
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20 min
2. An introduction to randomization for clinical trials 2- Prof. William Rosenberger
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42 min
3. Randomisation, blinding and drug supply in interactive voice response trials- Mr. Damian McEntegart
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42 min
4. Randomization in clinical trials: time for fresh consideration?- Dr. Alex Sverdlov
- Analysis
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32 min
5. Design and conduct of non-inferiority trials- Prof. Valerie Durkalski-Mauldin
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37 min
6. Nonparametric covariate adjustment- Prof. Michael Akritas
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34 min
7. The impact of randomization on the evidence of a clinical trial- Prof. Nicole Heussen
- Theory
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43 min
8. Historical and ethical issues in trial design- Dr. J. Rosser Matthews
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52 min
9. Likelihood ratios and the strength of statistical evidence- Prof. Jeffrey Blume
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36 min
- Randomization, Masking and Allocation Concealment
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22 min
11. Detection of and adjustment for selection bias in randomized controlled clinical trials- Prof. Lieven Nils Kennes
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46 min
12. Innovative and effective subject randomization methods- Prof. Wenle Zhao
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12 min
13. Selection bias in studies with unequal allocation- Dr. Olga M. Kuznetsova
- Archived Lectures *These may not cover the latest advances in the field
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45 min
14. Design and conduct of equivalence trials- Prof. Valerie Durkalski-Mauldin
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19 min
15. Dose-finding trials in oncology- Prof. Anastasia Ivanova
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32 min
16. Allocation concealment, prediction and selection bias- Prof. David Torgerson
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41 min
17. Pseudo cluster randomization- Dr. George Borm
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26 min
18. Introduction to flexible, adaptive trial design- Dr. Cyrus Mehta
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30 min
19. Randomization in clinical trials- Prof. William Rosenberger
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35 min
20. Novel methods for randomizing- Dr. William Grant
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20 min
21. Permutation tests- Dr. YanYan Zhou
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59 min
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32 min
23. Multiple analyses in clinical trials- Prof. Lemuel Moye
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26 min
24. Handling of missing data in clinical trials- Dr. Linda Yau
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35 min
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24 min
26. N-of-1 randomized clinical trials- Prof. Patrick Onghena
Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Population model vs. invoked population model
- The randomization model
- The importance of randomization
- Outline - restricted randomization procedures
- Randomization sequence
- Restricted randomization
- Forced-balance procedures
- Permuted block design
- Adaptive restricted procedures
- Efron's biased coin design
- Wei's urn design (1)
- Wei's urn design (2)
- Outline - stratification
- Stratification (1)
- Stratification (2)
- Stratification (3)
- Outline - randomization as a basis for inference
- Randomization as a basis for inference
- Unconditional and conditional tests
- Family of linear rank tests (1)
- Family of linear rank tests (2)
- Family of linear rank tests (3)
- Using randomization tests
- Why not use them?
- The Lindeberg condition
- Large-sample test statistic
- Outline - other forms of randomization
- Other forms of randomization (1)
- Other forms of randomization (2)
Topics Covered
- Randomization model for clinical trials and comparison to traditional sampling-based models
- Examples of randomization procedures used in practice
- Exploration of randomization as a basis for inference under the framework of the family of linear rank tests
- Randomization for the practicing biostatistician
Links
Series:
Categories:
Talk Citation
Rosenberger, W. (2007, October 1). Randomization in clinical trials [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 26, 2024, from https://doi.org/10.69645/DYYO2741.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. William Rosenberger, Other: Lecture materials based on scholarly textbook published with John Wiley and Sons, accrues royalties.
