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Printable Handouts
Navigable Slide Index
- Introduction
- Understanding genetics
- Definition of ethics
- Four principles
- Autonomy
- Beneficence
- Non-maleficence
- Justice
- Beneficence & non-maleficence
- Genetics
- Common ethical issues for families
- Determine the consultand’s agenda
- Testing an affected individual
- Confidentiality issues in genetic counselling
- Confidentiality
- Should families own genetic information?
- The “joint account model”
- Confidentiality e.g. Lynch syndrome, MLH1 mutation
- Issues with non-compliance
- Reasons for non-disclosure
- How genetic counsellors can help
- Test of an intermediate relative
- Testing children
- Genetic testing in children
- When to test children
- Testing in pregnancy
- Testing in pregnancy: dilemmas
- Prenatal diagnosis
- Genetic profiling of embryos
- The insurance dilemma
- Testing an unaffected person
- Population specific mutations
- Testing an unaffected person with deceased affected relatives
- Dilemmas
- Mutation detected in an unexpected gene
- Non-paternity
- Should genetic tests be more widely done?
- Emerging clinical indications
- Commercial genetic testing
- Genetic report card
- Clinical relevance
- Genome editing: CRISPR/Cas9
- The ability to alter the genetic code
- BRCA1 mutation
- Genome editing
- What is possible?
- Risks of germline genome editing
- What is desirable?
- Genetically modified babies: He Jiankui
- Who is the ideal person?
- A diverse society
- The needs of society
- Genetic elitism
- Regulations for genome editing
- Eugenics
- Eugenics: good and bad genes
- Thank you!
Topics Covered
- Principles of genetic counselling
- Confidentiality and ethical issues in genetic counselling
- Ownership of genetic information
- The role of genetic counsellors
- Genetic testing in children and during pregnancy
- Genetic testing of unaffected people
- Clinical relevance of genetic testing
- Genome editing and regulations
- Avoiding eugenic thinking
Links
Series:
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Talk Citation
Hodgson, S. (2021, January 31). Social and ethical issues in genetic counselling [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/MGPG2028.Export Citation (RIS)
Publication History
Financial Disclosures
- None
Other Talks in the Series: Introduction to Human Genetics and Genomics
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, I'm Shirley Hodgson.
I'm a cancer geneticist.
I've been working in cancer genetics really since 1980,
which is a long time,
mostly at Guy's and then more recently at St. George's Hospital,
and now I'm working part-time at
Leicester Royal Infirmary and doing clinics in cancer genetics.
I want to talk a little bit about the ethics of
the issues that we get involved within cancer genetic counseling,
and the way one approaches talking to people and trying to explain
the rather complicated issues about cancer genetics and general genetics also,
and then some of the more complicated ethical issues
that we can see coming at us from the future.
0:46
I've just put this slide up because, of course,
we always assume that people we talk to know exactly the sorts of
things that we know about genetics and genetics issues, but, of course,
other people may not have the same background and may not understand it in the same way,
and it's very important to try and step back a little bit as we talk to people to try and
get a feel for what they understand about
the issues that we're talking about rather than what we understand,
which is often quite difficult.
1:17
Just to start with,
I would like to just define ethics, in general.
It's thought to be a generic term for ways of understanding and examining the moral life.
1:30
The four principles of ethics are autonomy,
beneficence, non-maleficence, and justice.
Those all seem totally wonderful and good ideals and principles,
but of course, they don't always agree with each other.
You might find that one of them might actually
give you something which disagrees with the next one.