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1. Introduction
2. Main actors in Ca2+ homeostasis mechanism
3. Calcium signalling: dynamics and homeostasis
4. Genetic disorders of Ca2+ channels and pumps (1)
5. Events involved in a muscle twitch
6. Membrane potential vs. time
7. Neuro-muscular junction
8. Multimolecular calcium signalling complexes
9. Arrangement of proteins in SR and T tubule
10. Sarcoplasmic reticulum
11. Malignant hyperthermia
12. Central core disease (CCD)
13. Brody disease
14. Organisation of cardiac calcium signalling
15. Arrithmogenic right ventricular dysplasia 2-ARVD2
16. Genetic disorders of Ca2+ channels and pumps (2)
17. Structure of voltage-gated Ca2+ channels
18. Familial hemiplegic migraine (FHM)
19. Golgi can also be a Ca2+ storage compartment
20. Hailey Hailey disease
21. Mutation in Orai1 causes immune deficiency
22. Summary

Topics Covered

• General concepts of calcium signaling
• Mechanisms of calcium extrusion/uptake
• Mechanisms of calcium release from the ER/SR
• General concepts about plasma membrane calcium channels
• Genetic defects of calcium release channels
• Genetic defects of plasma membrane calcium channels
• Genetic defects of calcium pumps
• Novel findings on genetic defects of store dependent calcium channels

Links

Series:

• Calcium Signaling I
• Calcium Signaling II

Categories:

• Biochemistry
• Cell Biology

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Tullio Pozzan has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.