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- Research interviews
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1. The regulation of cell therapy
- Prof. Moutih Rafei
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2. How and why neurons die in Alzheimer's disease?
- Prof. Bart De Strooper
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3. The future of blood tests in cancer treatment
- Dr. Isaac Garcia-Murillas
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4. Role of marketing authorization holder in drug safety
- Dr. Raphael Elmadjian Pareschi
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5. Synthetic whole embryo models and their applications
- Prof. Jacob (Yaqub) Hanna
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6. Scale-up challenges in the production of nanomedicines from lab to industry
- Prof. Dr. Oya Tagit
-
7. Artificial intelligence in precision medicine
- Dr. Michael P. Menden
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8. Translational medicine: the risk of failure in delay and how to reduce it
- Prof. Martin Wehling
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9. Challenges and solutions of scaling up
- Dr. Shaukat Ali
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11. Management of generic drug development: challenges and opportunities
- Mr. Sandeep Patil
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12. MassBank development and future
- Dr. Emma L. Schymanski
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13. Elite controllers of HIV: from discovery to future therapies
- Prof. Bruce Walker
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14. Translational research in amyotrophic lateral sclerosis (ALS)
- Prof. Aaron D. Gitler
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16. PANDAS: a potential link between group A streptococcal infections and neurological disorders
- Prof. P. Patrick Cleary
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17. Rheumatic diseases and musculoskeletal pain
- Prof. Anisur Rahman
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18. Towards developing a universal influenza vaccine
- Prof. Peter Palese
- Clinical interviews
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19. Monkeypox: etiopathogenesis, prevention, and treatments
- Dr. Dennis Hruby
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20. Kidney xenotransplantation
- Dr. Douglas J. Anderson
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21. CAR-T and TCR-T cellular immunotherapies in oncology
- Prof. Sebastian Kobold
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22. MAPS: the business of medical affairs
- Dr. Danie du Plessis
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23. Hypertrophic cardiomyopathy: therapies and treatments
- Prof. Srihari Naidu
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24. Combating the HIV epidemic
- Prof. William Blattner
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25. Epigenetic pharmaceuticals used in the clinic
- Dr. Thomas Paul
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26. Precision cancer medicine: development and future
- Prof. Maurie Markman
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27. Pediatric cancer testing
- Prof. Joshua Schiffman
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28. Opposition to vaccination: a transatlantic discussion
- Prof. Jonathan Temte
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29. Elective caesarean sections from an evolutionary perspective
- Prof. Wenda Trevathan
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30. Antiphospholipid syndrome and Lupus
- Prof. Graham Hughes
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31. Prescribing medications to children - a GP’s view
- Dr. Amanda Simmons
Topics Covered
- What is MassBank?
- Difficulties in the development and continuation of MassBank
- How the ensure quality of data
- Formatting and validation data
- Representing structural uncertainty
Biography
Dr. Emma Schymanski is a research scientist at Eawag, the Swiss Federal Institute for Aquatic Science and Technology. She develops suspect, non-target and unknown identification methods for environmental contaminants, primarily with LC-HRMS/MS. Contributing mass spectra to open spectral libraries is an essential part of this work and she is an active member of the MassBank consortium, developing RMassBank in a team.
Talk Citation
Schymanski, E.L. (2020, April 21). MassBank development and future [Audio file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/LRLL3548.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Emma L. Schymanski has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Methods
Transcript
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0:00
Interviewer: Dr. Emma Schymanski,
thank you very much for
taking the time to discuss MassBank,
perhaps let's start with a brief
description of MassBank and
your role in it.
Dr. Schymanski: MassBank
is an open spectral library,
it was designed originally for
the metabolomics field,
we have now taken it and extended it
a bit for the environmental field.
It's made up of spectra from all around
the world, we have contributors in several
different countries and we now have
three servers: the Japanese server (the
original), the European server which
I've been involved with since 2012 and
also recently an American server,
run by Oliver Finn and his group.
My main role in MassBank is to expand
this towards the environmental community,
to share the data between a lot of members
of what we call the NORMAN Network,
which is an environmental
community in Europe.
We can exchange our spectra and
our knowledge between our members and
also around the world so
people can improve the identification
of environmental contaminants.
At the same time we're also
developing tools for metabolomics,
and working with other
spectral libraries beyond
MassBank towards exchanging this
information around the world.
Interviewer: Excellent thank you.
What are the challenges in getting the
scientific community to contribute to this
database?
Are there any steps that are taken from
your end to encourage more contributions?
Dr. Schymanski: We've found
throughout the years that we've been
involved that there's a lot of resistance
to contributing, and this is actually for
many reasons.
Mostly, it's just time, people would
like to but they don't have time, so
some of the steps here are trying
to develop tools and methods for
people to be able to contribute their
data more quickly or in an easier way.
We've had mixed success with some
of the tools, we've developed
some great interfaces that are still
very complicated for people to use.