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Printable Handouts
Navigable Slide Index
- Introduction
- Contents: Epidemiology
- Neurological disorders: leading cause of disability adjusted life (DALY'S)
- Main common risk and protective factors for stroke and dementia
- Correlated decline in stroke and dementia incidence after stroke-prevention strategy
- Contents: Pathology and prathophysiology
- Distribution of primary neuropathologies
- Prevalence of infarcts in patients with cerebrovascular disease: Rotterdam study
- STRIVE: Standards for reporting and imaging of small vessel disease
- PET scanning to measure cerebral amyloid
- Head trauma is an important risk for Alzheimer’s and another dementia
- Vascular risk and beta-amyloid burden
- Vascular risk and beta-amyloid are in synergistic association with cortical tau
- Preliminary data and survivability
- White matter inflammation as a predictor of post-stroke cognitive status
- Contents: Prevention
- Association of cardiovascular health level and dementia
- Atrial fibrillation, anticoagulation and dementia
- Systolic blood pressure and dementia
- ApoE4 blood flow and white matter damage
- Main common risk and protective factors for stroke and dementia (2)
- Correlated decline in stroke and dementia incidence after stroke-prevention strategy (2)
- Contents: From evidence to action
- Promotion of World Stroke Day
- Updated stroke and dementia proclamation
- Implementing the Proclamation of Stroke and Potentially Preventable Dementias
- Dementia prevention by stroke prevention
- Trends
- Conclusions
- Thank you!
Topics Covered
- Epidemiology
- Neurological disorders leading causes of DALY’s
- Common risk and protective factors of stroke and dementia
- Concomitant decrease of stroke and dementia
- Interaction of vascular and neurodegenerative mechanisms
- Joint prevention of stroke and dementia
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Talk Citation
Hachinski, V. (2019, October 31). Convergence and joint prevention of stroke and dementia [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 4, 2024, from https://doi.org/10.69645/OAHZ4871.Export Citation (RIS)
Publication History
Financial Disclosures
- Professor Vladimir Hachinski has no commercial/financial relationships to disclose
A selection of talks on Clinical Practice
Transcript
Please wait while the transcript is being prepared...
0:00
I'm Vladimir Hachinski,
Distinguished University Professor at Western University, London, Canada.
The topic that we're covering is
the "Convergence and Joint Prevention of Stroke and Dementia".
0:16
We will cover the epidemiology, the pathology,
and pathophysiology, prevention, and then go from the evidence to action.
0:28
To put it in perspective,
it turns out that globally,
neurological disorders now are the leading cause of DALYS.
DALYS are disability-adjusted life years which
means premature death and years spent in disability.
By now, 10 percent of the world's DALYs are due to neurological disorders.
Then among neurological disorders,
stroke accounts for 42 percent and dementia for 10 percent,
together accounting for more than half of neurological DALYs in the world.
1:07
Luckily, the risk factors for both are the
same and many of them are treatable and preventable,
that includes cerebrovascular disease and stroke,
cardiovascular disease, hypertension, high cholesterol,
obesity, diabetes, smoking, homocysteine,
stress, depression, and atrial fibrillation.
In addition to risk factors,
there also are protective factors: high education,
physical activity, antihypertensives, statins,
an active lifestyle, the Mediterranean diet, and anti-coagulation.