I'm Vladimir Hachinski,
Distinguished University Professor at Western University, London, Canada.
The topic that we're covering is
the "Convergence and Joint Prevention of Stroke and Dementia".
We will cover the epidemiology, the pathology,
and pathophysiology, prevention, and then go from the evidence to action.
To put it in perspective,
it turns out that globally,
neurological disorders now are the leading cause of DALYS.
DALYS are disability-adjusted life years which
means premature death and years spent in disability.
By now, 10 percent of the world's DALYs are due to neurological disorders.
Then among neurological disorders,
stroke accounts for 42 percent and dementia for 10 percent,
together accounting for more than half of neurological DALYs in the world.
Luckily, the risk factors for both are the
same and many of them are treatable and preventable,
that includes cerebrovascular disease and stroke,
cardiovascular disease, hypertension, high cholesterol,
obesity, diabetes, smoking, homocysteine,
stress, depression, and atrial fibrillation.
In addition to risk factors,
there also are protective factors: high education,
physical activity, antihypertensives, statins,
an active lifestyle, the Mediterranean diet, and anti-coagulation.