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- Perspective and Pathogenesis
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1. Expanding frontiers of cerebrovascular disease
- Prof. Vladimir Hachinski
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2. Basic anatomy, physiology and pathophysiology of the cerebral circulation for the physician
- Prof. Jean-Claude Baron
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3. Pathophysiology of cerebral ischemia
- Prof. Wolf-Dieter Heiss
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4. Intracerebral hemorrhages: causes and clinical findings
- Prof. Louis Caplan
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5. Subarachnoid hemorrhage (SAH)
- Prof. R. Loch Macdonald
- Diagnosis
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6. Clinical diagnosis of stroke and subtypes
- Prof. Louis Caplan
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7. The investigation of stroke
- Dr. Bart Demaerschalk
- Treatment
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8. Acute therapy of stroke and reperfusion treatments
- Prof. Brian Silver
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9. Subarachnoid hemorrhage diagnosis and management
- Prof. Gary K. Steinberg
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10. Stroke-induced heart injury
- Dr. Luciano A. Sposato
- Rehabilitation
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11. Stroke rehabilitation: principles of stroke
- Prof. Robert Teasell
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12. Stroke rehabilitation: therapies and treatments
- Prof. Robert Teasell
- Prevention
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13. Lifestyle and nutrition in stroke prevention
- Prof. J. David Spence
- Special Topics
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15. Pediatric stroke: cerebrovascular injury in the developing brain
- Prof. Adam Kirton
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16. Stroke in women: epidemiology, risk and prevention
- Prof. Cheryl Bushnell
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17. Transient ischemic attack and cognition
- Dr. Jennifer Mandzia
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18. Vascular cognitive impairment
- Prof. Eric E. Smith
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19. Atrial fibrillation, anticoagulation and vitamins for homocysteine
- Prof. J. David Spence
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20. Stroke in the young adult
- Prof. Jeffrey Saver
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21. Stroke in the young
- Dr. Gyan Kumar
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22. Convergence and joint prevention of stroke and dementia
- Prof. Vladimir Hachinski
- Archived Lectures *These may not cover the latest advances in the field
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23. Vascular cognitive impairment
- Dr. John Bowler
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24. Pediatric stroke
- Dr. Gabrielle deVeber
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25. The deteriorating stroke
- Prof. Werner Hacke
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26. General management
- Prof. Bo Norrving
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27. The treatment of stroke: specific management - thrombolysis plus
- Prof. Nils Wahlgren
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28. Rehabilitation: the chronic phase
- Prof. Lalit Kalra
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29. Prevention: management of risk and protective factors
- Prof. Graeme Hankey
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30. Medical therapy for secondary prevention of ischemic stroke
- Prof. Larry Goldstein
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31. Subarachnoid haemorrhage
- Prof. Jan van Gijn
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32. Controversies in stroke
- Prof. Stephen Davies
- Prof. Geoffrey Donnan
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33. Medical and surgical stroke
- Prof. Carlos Kase
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34. The urgency of stroke prevention after TIA
- Prof. S. Claiborne Johnston
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35. Carotid endarterectomy, angioplasty and stenting
- Prof. Martin Brown
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36. The clinical diagnosis of stroke and stroke subtypes
- Prof. Louis Caplan
Printable Handouts
Navigable Slide Index
- Introduction
- Disclosures
- Stroke prevention: keep drugs in perspective
- Importance of lifestyle
- Healthy lifestyle reduced stroke in Swedish women
- Healthy lifestyle reduced CAD in Swedish men
- Managing stroke risk factors
- Nutrition in stroke prevention
- Foods and nutrients that are good for the brain
- Flax seed strains with phytoestrogen
- Naringenin reduces insulin resistance
- Nobiletin prevents diet-induced obesity
- Nobiletin & atherosclerotic plaque formation
- Fruits and vegetables reduce mortality
- Antioxidant supplements don’t work
- Antioxidants give colour and flavour
- So what works?
- Fat and heart disease
- The “good” Mediterranean diet
- Lyon diet heart study
- Spanish Mediterranean diet study
- Dietary cholesterol is important
- The 2015 US cholesterol guidelines
- Diet is the worst part of US lifestyle
- A diet high in animal fat is not the answer!
- Sick populations
- Egg yolks and CHD risk
- Egg yolks
- Saturated fat in meat
- Intestinal microbiome and diet
- TMAO increases stroke/death/MI
- Survival free of atherosclerotic events (egg intake)
- Most North Americans will be vascular patients
- Dietary recommendations for vascular patients
- B vitamins to lower homocysteine
- tHcy≥14 μmol/L by age
- VISP efficacy analysis
- B-Vitamin therapy
- Stroke, MI, death
- Folic acid reduces stroke in 1° prevention
- Results of B vitamin trials
- Meta-analysis: renal function, cyanocobalamin
- Cyanide in cyanocobalamin
- Interesting lessons
- Good news
- Chocolate consumption
- Acknowledgments
Topics Covered
- Stroke risk factors overview and management
- Mediterranean diet benefits in stroke prevention
- Intestinal microbiome and diet effect on atherosclerosis
- Dietary recommendations for vascular patients
- B Vitamins in stroke prevention
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Spence, J.D. (2017, December 31). Lifestyle and nutrition in stroke prevention [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 13, 2024, from https://doi.org/10.69645/NNHX6620.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. J. David Spence has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Pharmaceutical Sciences
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, I'm David Spence.
I'm professor of neurology and
clinical pharmacology at Western University in London Canada,
and Director of the Stroke Prevention and Atherosclerosis Research Center.
This talk is about lifestyle and nutrition in stroke prevention.
0:17
When disclosures are on this slide and none is relevant to this talk.
0:23
In thinking about stroke prevention it's important to keep
medication which most doctors seem to emphasize in perspective,
medication is only a small part of stroke prevention,
and lifestyle is much more important than most doctors think it is.
When we rank the things we can do to prevent stroke in order of importance,
it's likely that smoking cessation and a Mediterranean diet would rank near the top.
0:47
So, the importance of lifestyle was demonstrated in
this study from the US Public Health study,
and the Nurses Health Study,
43,000 men and 71,000 women followed.
And what this study reported was that persons who followed all healthy lifestyle choices,
which were not smoking,
a moderate intake of alcohol,
a body mass index less than 25,
daily exercise of 30 minutes,
and a diet scored in the top 40 percent had a reduction of stroke by 80 percent.
Now, that was in unhealthy Americans.
1:22
Among Swedish women, Swedish people may be more healthy than Americans.
So, a healthy lifestyle reduced stroke by
62 percent among Swedish women who were healthy at the beginning.
1:35
In Swedish men with hypertension and hyperlipidemia,
all five healthy lifestyle choices
reduced coronary artery disease by more than 80 percent.
So, lifestyle is hugely important.