Transport mechanism of urate in humans

Published on May 31, 2016   52 min

Other Talks in the Series: Topical Talks

0:00
Hello, my name is Hiroyuki Saturai, professor of pharacology, Kyorin University School of Medicine, Tokyo, Japan. Today, I'd like to discuss urate transport in our body. I will try hard to explain physiological principles of urate transport so that my talk is applicable not only to urate, but also to many negatively charged xenobiotics or endogenous substrate.
0:29
So this is the agenda for this talk. I will briefly discuss about what urate is doing in our body. Then we move to the physiology of trans-epithelial movement of the solute. Then I will come back to urate handling and especially in the two key organs in urate metabolism, kidney and the intestine. Then I will finish with drugs that affect urate transport, either a treatment or a side effect.