Lens development and disorders - clinical diagnosis and treatment

Published on May 31, 2016   31 min
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This is the second lecture dealing with lens development and lens development disorders. My name is Professor Chris Lloyd. I'm a consultant ophthalmologist at Great Ormond Street Hospital in London. I'm also an honorary consultant at Manchester Royal Eye hospital and honorary professor of pediatric ophthalmology at Manchester Academic Health Sciences Center in the University of Manchester.
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Congenital aphakia is an extremely rare malformation of the eye. It's usually associated with other ocular malformations. It can be caused by rubella syndrome or other early teratogenic influences during the first four weeks of gestation. It can be caused by homozygous mutations in the FOXE3 gene, as illustrated by the graphic to the right. This is a case that was published in Molecular Vision six years ago. It can also occur as a secondary phenomenon due to persistent fetal vasculature.
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Lens development and disorders - clinical diagnosis and treatment

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