• The Apoptotic Pathway in Humans
• 36 min
  1. Mitochondria and apoptosis

  • Prof. Stephen Tait
• Clinical Application of Apoptosis Research
• 31 min
  2. Targeting apoptosis pathways in cancer therapy

  • Dr. Simone Fulda
• Archived Lectures *These may not cover the latest advances in the field
• 42 min
  3. Targeting apoptosis pathways in cancer therapy

  • Dr. Irene Ghobrial
• 20 min
  4. Apoptotic pathways in mammals

  • Prof. Douglas Green
• 46 min
  5. Lysosomal cell death pathways: new possibilities for cancer therapy

  • Prof. Marja Jaattela
• 57 min
  6. Degradation of apoptotic cells

  • Prof. Shigekazu Nagata
• 61 min
  7. Signaling during engulfment: the beginnings of a good meal

  • Prof. Kodi Ravichandran
• 29 min
  8. Apoptotic cell clearance deficiencies

  • Prof. Martin Herrmann
• 46 min
  9. Caspase inhibitors in drug discovery

  • Dr. Tom O'Brien
• 28 min
  10. Mitochondria in apoptosis

  • Prof. Jean-Claude Martinou
• 52 min
  11. Apoptosis in C. elegans

  • Prof. Michael Hengartner
• 46 min
  12. Regulation of apoptosis: lessons from Drosophila and their implications for human health and disease

  • Prof. Hermann Steller
• 29 min
  13. The death receptor signalling pathway

  • Dr. Richard Siegel
• 24 min
  14. The Bcl-2 family

  • Dr. David Huang
• 43 min
  15. Caspases

  • Prof. Yuri Lazebnik
• 44 min
  16. Mechanisms of apoptosis from structural biology

  • Prof. Yigong Shi
• 64 min
  17. p53 and apoptosis

  • Prof. Moshe Oren
• 47 min
  18. The p53 family: function and molecular mechanisms

  • Prof. Gerry Melino
• 37 min
  19. Natural caspase inhibitors

  • Prof. Guy Salvesen
• 27 min
  20. TRAIL-induced apoptosis: from analysis of the death-inducing signalling complex (DISC) to clinical applicability

  • Dr. Henning Walczak
• 34 min
  21. Autophagic cell death

  • Prof. Eric Baehrecke
• 28 min
  22. Phagocytosis of apoptotic cells

  • Prof. Peter Henson
• 62 min
  23. Apoptosis in the immune system

  • Prof. Peter Krammer
• 68 min
  24. Apoptosis in the nervous system

  • Prof. Pierluigi Nicotera
• 49 min
  25. Endothelial cell apoptosis

  • Prof. Richard Kolesnick

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Tissue homeostasis: the balance of life and death
3. Apoptosis in cancer therapy (1)
4. Apoptosis pathways
5. Targeting death receptors for cancer therapy
6. Targeting the intrinsic pathway of apoptosis
7. Bcl-2 family proteins
8. Targeting bcl-2 proteins for cancer therapy
9. Caspase inhibition by IAPs (1)
10. Caspase inhibition by IAPs (2)
11. Targeting IAPs for cancer therapy
12. Apoptosis in cancer therapy (2)

Topics Covered

• Apoptosis in cancer
• Apoptosis signalling pathways
• Death receptor pathway
• Mitochondrial pathway
• Targeting the death receptor pathway
• Bcl-2 family proteins: structure and function
• Targeting Bcl-2 family proteins
• IAPs: structure and function
• Targeting IAPs

Links

Series:

• Apoptosis

Categories:

• Cancer
• Cell Biology

Therapeutic Areas:

• Immunology & Inflammation
• Oncology

Talk Citation

Publication History

• Published on October 1, 2007
• Reviewed on November 22, 2019

Financial Disclosures

• Dr. Simone Fulda has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.