I'm Paola Giunti, and I'm
the head of the Ataxia Center
at UCLH at Queen's Square, London.
And today, I'm going to talk
about the Inherited Ataxias.
First of all, I would like to
talk about what ataxia means.
So ataxia is a Greek word
and "a" stands for absence
and "taxia" stands for coordination.
So basically, ataxia is lack of
order and lack of coordination.
The main feature is
the loss of balance
that produces unsteadiness
gate with swaying and risk of falls.
Limb movements are also
involved in this doses process.
And they can become
and there is evidence of tremor.
The eye movement are interrupted.
There Is what we call nystagmus
and the fixation may be unstable.
So that creates double
vision for the patient.
The speech becomes slurred and
the speed and volume is altered.
Inherited ataxias can be congenital,
episodic, or progressive.
And the inheritance may be autosomal
dominant, recessive, or x-linked.
Also we have a
mitochondrial in this disorder.