• Evolutionary Perspectives
• 42 min
  1. Antibiotic resistance: a mechanistic overview

  • Dr. Neil Woodford
• 20 min
  2. Mutation

  • Prof. Stephen Gillespie
• 11 min
  3. Fitness in antibiotic resistant bacteria

  • Prof. Stephen Gillespie
• 34 min
  4. Fitness and compensation

  • Dr. Sébastian Gagneux
• 22 min
  5. Antibiotic resistance and the supragenome hypothesis

  • Dr. Bambos Charalambous
• Epidemiology and Clinical Impact
• 37 min
  6. Methicillin resistant S. aureus and other resistances

  • Prof. Mark Enright
• 43 min
  7. Risk factors for antibiotic resistance in Streptococcus pneumoniae

  • Prof. Keith Klugman
• 38 min
  8. Beta-lactamases: clinical impact and epidemiology

  • Prof. Sebastian Amyes
• 49 min
  9. Glycopeptide-resistant enterococci

  • Dr. Neil Woodford
• 33 min
  10. Drug resistant tuberculosis: biology, epidemiology and control

  • Dr. Christopher Dye
• 26 min
  11. Antiretroviral drug resistance

  • Prof. Deenan Pillay
• 49 min
  12. Malaria - changing paradigms

  • Dr. Janet Cox-Singh
• 42 min
  13. Advances in mode of action of antimalarials and resistance mechanisms 1

  • Prof. David Warhurst
• 38 min
  14. Advances in mode of action of antimalarials and resistance mechanisms 2

  • Prof. David Warhurst
• Diagnosis and Surveillance of Resistance
• 29 min
  15. Conventional and automated diagnostic methods

  • Dr. Alan Johnson
• 38 min
  16. National and international surveillance of antibiotic resistance 1

  • Prof. David Livermore
• 50 min
  17. National and international surveillance of antibiotic resistance 2

  • Prof. David Livermore
• 24 min
  18. Innovative approaches to rapid antibiotic resistance testing

  • Dr. Robert Hammond
• Controlling Antibiotic Resistance
• 39 min
  19. Controlling antibiotic resistance in the hospital environment

  • Dr. Ian Eltringham
• 27 min
  20. Controlling antibiotic resistance in the community

  • Dr. Peter Wilson
• 51 min
  21. Public policy to reduce antibiotic resistance

  • Dr. Niels Frimodt-Møller
• The Antibiotic Resistance Future
• 26 min
  22. Overcoming resistance through novel drug targets

  • Prof. Anthony Coates
• 37 min
  23. Medicinal chemistry strategies in combating antibiotic resistance

  • Dr. Geoffrey Coxon
• 36 min
  24. Teixobactin kills pathogens without detectable resistance

  • Prof. Kim Lewis
• Archived Lectures *These may not cover the latest advances in the field
• 48 min
  25. Molecular diagnosis of antibiotic resistance

  • Dr. Tim McHugh
• 36 min
  26. Introduction to malaria

  • Prof. David Warhurst

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Life cycle stage as drug target
3. Malaria parasite in red blood cell
4. Action of antiplasmodial drugs
5. Chloroquine base is trapped in acidic DV
6. Targets other than DV
7. Sdx and Pyr targets in the folate synthesis cycle
8. Resistance to sulfadoxine and pyrimethamine
9. Mitochondrial compartment
10. CoQ8 and atovaquone similarity
11. Cytochrome B wild type vs. mutant
12. Apicoplast
13. Cultured pre-erythrocytic schizont of P. berghei
14. CQ, QN, mefloquine, artemisinin & analogues
15. Sweet wormwood (Artemisia annua) (1)
16. Sweet wormwood (Artemisia annua) (2)
17. Artemisinin structure and metabolism
18. Artemisinin mode of action
19. Evidence for drug activation

Topics Covered

• Life cycle stage as drug target
• Action of antiplasmodial drugs
• The digestive vacuole
• Resistance to sulfadoxine and pyrimethamine
• Artemisinin mode of action

Links

Series:

• Antibiotic Resistance

Categories:

• Clinical Practice
• Microbiology
• Pharmaceutical Sciences

Therapeutic Areas:

• Infectious Diseases

Talk Citation

Publication History

• Published on November 6, 2013

Financial Disclosures

• Prof. David Warhurst has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.