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Navigable Slide Index

1. Introduction
2. Introductory comments
3. Standard operating procedures
4. Maintenance
5. Equipment failure
6. Only a small number of instruments are critical
7. Reliability-centred maintenance
8. GLP inspector should check all SOPs available
9. Stick to the GLP principles!
10. Major types of technical equipment
11. General-purpose devices
12. Physical-chemical apparatuses
13. Analytical instrumentation
14. Examples of analytical techniques
15. Scheme of an LC-ICP-MS system, example 1
16. Scheme of an LC-ICP-MS system, example 2
17. Scheme of an LC-ICP-MS system, example 3
18. Inspector need to assess use & maintenance
19. Scope of method validation
20. Validation refers to analytical systems
21. Each system has a specific field of application
22. Validation procedures
23. Method performance characteristics
24. System validation and GLP inspections
25. Check-list of validation items
26. Inspector should ask for documented evidence
27. The ultimate goal of validation
28. Suitability of equipment
29. Concentrate on aspects where errors are greatest
30. Method development, optimization, validation
31. Inspector must check validated methods in place
32. GLP validation is more expensive
33. Validity depends on reliability of information
34. Technical personnel
35. The TFM
36. The policy of the TFM

Topics Covered

• Analytical chemistry
• Calibration of analytical equipment
• Failure of equipment
• Hyphenated analytical techniques
• Inspections of Good Laboratory Practice-compliant test facilities
• Integrity of studies
• Maintenance of analytical equipment
• Physical-chemical apparatuses
• Principles of Good Laboratory Practice
• Standard Operating Procedures
• Validation of analytical systems

Links

Series:

• Good Laboratory Practice

Categories:

• Methods
• Pharmaceutical Sciences

Talk Citation

Caroli, S. (2013, July 18). The application of the GLP principles in analytical chemistry [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 21, 2024, from https://doi.org/10.69645/KQJZ5929.
Export Citation (RIS)

Publication History

• Published on July 18, 2013

Financial Disclosures

• Prof. Sergio Caroli has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.