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1. Streptococcus pneumoniae: serotype diversity and epidemiology
- Dr. Bambos Charalambous
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2. Tuberculosis: new treatments in evolution
- Prof. Stephen Gillespie
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3. Current drugs for TB treatment
- Dr. Kasha Singh
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4. Global progress in TB vaccine development
- Prof. Helen McShane
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5. Management of MDR and XDR TB
- Prof. Martin Boeree
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6. Non-tuberculous mycobacterial pulmonary disease (NTM-PD)
- Prof. Jakko van Ingen
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7. The making of an influenza pandemic
- Prof. Jonathan Van-Tam
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8. Responding to pandemic influenza
- Prof. Jonathan Van-Tam
- Dr. Chloe Sellwood
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9. Controlling pandemic flu
- Prof. John Oxford
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10. The future of influenza vaccines
- Dr. Marc P. Girard
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11. Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide
- Dr. Marietjie Venter
- Mrs. Orienka Hellferscee
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12. RSV vaccine development
- Prof. Ruth Karron
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13. Respiratory mycoplasmas
- Prof. Stephen Gillespie
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14. Infection in the cystic fibrosis lung
- Dr. Stuart Elborn
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15. The role of infection at COPD exacerbations
- Prof. Wisia Wedzicha
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16. An overview of non-cystic fibrosis bronchiectasis
- Dr. Maeve P. Smith
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18. Pathogen discovery in the respiratory tract
- Dr. H. Rogier van Doorn
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19. Aspergillosis infections and the lung
- Prof. Rosemary Barnes
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20. Parasitic lung infections: protozoa, cestodes & trematodes
- Dr. Vannan Kandi Vijayan
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21. Parasitic lung infections: nematodes
- Dr. Vannan Kandi Vijayan
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22. Improving respiratory diagnostics (viruses)
- Prof. David Murdoch
Printable Handouts
Navigable Slide Index
- Introduction
- COPD exacerbations
- Airway bacteria - stable COPD & exacerbations (1)
- RCT of antibiotic therapy
- Sputum characteristics
- Bacterial eradication & inflammation
- Changes in bacterial load
- Risk of exacerbation & bacterial strain change
- Strain change & bacterial load relationship
- Lung microbiome in smoker vs. COPD (1)
- Lung microbiome in smoker vs. COPD (2)
- Respiratory viruses & exacerbation
- Exacerbation recovery after onset
- HRV and COPD exacerbations
- Effect of common colds on IL6 in induced sputum
- Plasma fibrinogen at exacerbation
- Exacerbation frequency & common cold in COPD
- Susceptibility of COPD patients to rhinovirus
- Eosinophilic markers of viral exacerbations
- Lower airway bacteria & rhinoviral infection
- Sputum IL1B at bacterial exacerbations
- Change in IP10 from baseline to exacerbation
- IP10 ROC curve analysis
- Airway bacteria - stable COPD & exacerbations (2)
- Bacterial load & airway inflammation
- Airway bacterial load & FEV1 decline
- Lower lobe bronchiectasis - COPD & inflammation
- Doxycycline vs. placebo (1)
- Doxycycline vs. placebo (2)
- Exacerbation frequency & bacterial colonization
- Long term antibiotics
- Patients with purulent/mucopurulent sputum
- Macrolides - time to 1st exacerbation
- Macrolides - sputum markers
- Macrolide (Azithromycin) study
- Macrolide study - subgroup analysis
- RSV infection in stable COPD
- Patterns of RSV infection
- RSV & FEV1 decline
- High sputum myeloperoxidase in COPD with RSV
- Conclusion
Topics Covered
- Roles of viral and bacterial infections at exacerbations of COPD
- Airway bacteria
- RCT of antibiotic therapy
- Sputum characteristics
- Bacterial eradication & inflammation
- Bacterial strain change
- Lung microbiome in smoker vs. COPD
- Plasma fibrinogen at exacerbation
- Exacerbation frequency & common cold in COPD
- Rhinovirus
- Eosinophilic markers of viral exacerbations
- Lower lobe bronchiectasis
- Doxycycline vs. placebo
- Long term antibiotics
- Patients with purulent/mucopurulent sputum – Macrolide studies
- RSV infection in COPD
Links
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Talk Citation
Wedzicha, W. (2013, July 11). The role of infection at COPD exacerbations [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved January 2, 2025, from https://doi.org/10.69645/KJGU9442.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Wisia Wedzicha has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.