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- Introduction
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1. Psychopharmacology: structural aspects of the brain
- Prof. Brian Leonard
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2. The nature of chemical neurotransmission
- Prof. Brian Leonard
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3. Psychotropic drugs
- Prof. Brian Leonard
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4. Psychopharmacology of anxiety disorders
- Prof. Brian Leonard
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5. Psychopharmacology of depression
- Prof. Brian Leonard
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6. Psychopharmacology of mania and schizophrenia
- Prof. Brian Leonard
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7. The role of stress and immune system in psychiatric disorders
- Prof. Brian Leonard
- Introduction to Genetic Investigations of Complex Traits
- Genetics and Pharmacokinetics of Psychotropic Drugs
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9. Genetics of phase I enzymes
- Prof. Aiming Yu
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10. Phase II metabolism
- Prof. Ann Daly
- Genetics and Pharmacodynamics of Psychotropic Drugs
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13. Pharmacogenetics of antidepressants
- Prof. Alessandro Serretti
- Clinical Applications of Psychopharmacogenetics
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14. Of genes and drugs: genetic determinants of adverse drug reactions
- Dr. Mario Masellis
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15. Cocaine and amphetamine addiction genetics
- Dr. Gerome Breen
- Archived Lectures *These may not cover the latest advances in the field
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18. Genetic determinants of metabolism: clinical applications in psychiatry
- Prof. Julia Stingl (formerly Kirchheiner)
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20. Genetic polymorphisms influencing response to lithium
- Prof. Alessandro Serretti
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21. Genetic determinants of antipsychotic-induced weight gain
- Prof. Gavin Reynolds
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24. Genetic determinants of agranulocytosis
- Dr. Michael Dettling
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25. Genetic polymorphisms influencing the response of antidepressants
- Prof. Alessandro Serretti
Printable Handouts
Navigable Slide Index
- Introduction
- Symptoms of depression
- Noradrenergic pathways in depression
- Serotonergic pathways in normal brain
- Serotonergic pathways in depression
- Desirable drug - effective in all types of depression
- Desirable features of a drug - rapid onset of action
- Desirable features of an antidepressant
- Psychopathology of depression and drugs used
- Amine deficiency hypothesis
- Neurotransmitters involved in depression
- Treatment and adaptive changes
- Classification of european antidepressants
- MAO inhibitors
- Reuptake inhibitors
- Nonselective reuptake inhibitors
- Selective reuptake inhibitors
- Other antidepressants
- Selectivity of transmitter uptake inhibitors
- Cross-talk between the neurotransmitters
- Sites of action of tricyclics on neuron
- Sites of action of MAO inhibitors
- Electroconvulsive shock therapy
Topics Covered
- Noradrenergic pathways in depression
- Serotonergic pathways in normal brain and in depression
- Desirable features of an antidepressant
- Drugs used in the treatment of depression
- Classification of antidepressants
- Tricyclic antidepressants and monoamine
- Oxidase inhibitors: sites of action
- The relationship between pre- and post-synaptic structures
- Electroconvulsive shock therapy
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Leonard, B. (2007, October 1). Psychopharmacology of depression [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/ZTMM9663.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Brian Leonard has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.