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1. Introduction
2. Motivation: tissue regeneration
3. The tissue engineering approach
4. Properties of an ideal scaffold (1)
5. Properties of an ideal scaffold (2)
6. Biomedical materials
7. Non-Bioresorbable materials
8. Non-bioresorbable polymers
9. Use of donor material
10. Bone graft materials
11. Bioresorbable polymers (1)
12. Bioresorbable polymers (2)
13. The biodegradation curve
14. Biomaterial properties
15. Bioactive glasses
16. Possible scaffold materials
17. Choosing scaffold materials
18. Fabrication of porosity
19. Foam bioglass scaffolds
20. Rapid prototyping
21. 3D characterisation
22. Biological response
23. Growth factor incorporation
24. Hierarchy of bone
25. Scaffold hierarchies
26. Nanofibre scaffolds
27. Natural self assembly
28. Designer peptide self assembly
29. Synthetic peptide hydrogels
30. Amphiphilic assembly
31. Finding cell binding domains
32. Synthesising peptides
33. Incorporating peptides
34. Incorporating of laminin IKVAV domain
35. Direct incorporating of the peptides
36. Polymer-protein hybrid scaffolds
37. PEG crosslinked onto the protein fragment
38. The extracellular environment
39. Nature's nanotechnology
40. Dynamic Maps
41. The body as a bioreactor
42. Further considerations
43. Wide ranging benefits
44. Summary
45. Further reading (1)
46. Further reading (2)
47. Further reading (3)
48. Figure references (1)
49. Figure references (2)
50. Figure references (3)

Topics Covered

• Range of materials considered for tissue engineering
• Research into cell-material interaction
• Development of new technologies
• Highly tailored biomaterials: role in guiding cell behaviour and tissue regeneration
• Medical implants
• The use of commonly available clinical bioresorbable polymers
• The use of bioactive materials: Bioglass
• Utilising self-assembling nanoscale fibres, peptide functionalisation and recombinant DNA technology
• Replication of structure and function of natural tissue
• Importance of production techniques to control material macro and nano structure

Links

Series:

• Stem Cells and Regenerative Medicine

Categories:

• Cell Biology
• Methods

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Dr. Molly Stevens has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
• Mr. Julian George has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.