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- Stem Cells
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1. Stem cells: immortality or a healthy old age?
- Dr. Jim McWhir
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2. Mouse embryonic stem cells
- Prof. Sir Martin Evans
- Regenerative Medicine (I)
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3. Stem cells and regenerative medicine
- Prof. Dame Julia Polak
- Dr. Anne Bishop
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4. Tissue engineering: the science, the technology and the industry
- Prof. Robert Nerem
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5. Clinical potential of stem cells
- Prof. John Martin
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6. Genes and cells therapy
- Prof. Nagy Habib
- Regenerative Medicine (II)
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7. Stem cell therapy for the treatment of heart failure
- Dr. James Willerson
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8. Vascular tissue engineering
- Prof. Robert Nerem
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9. Stem cell biology and neurodegenerative diseases
- Dr. Ronald McKay
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10. Cartilage stem cells: tools for joint repair?
- Prof. Charles Archer
- Biotechnology
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11. Stem cell bioprocessing
- Dr. Sakis Mantalaris
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12. Nanotechnology for tissue engineering
- Prof. Thomas J. Webster
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13. Materials for tissue engineering
- Dr. Molly Stevens
- Mr. Julian George
- Commercialization
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14. Commercialisation of stem cells
- Dr. Gareth Roberts
- Ethical and Regulatory Considerations
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15. Stem cell ethics
- Prof. Dame Anne McLaren
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16. The human fertilisation and embryology authority
- Dame Suzi Leather
- Archived Lectures *These may not cover the latest advances in the field
Printable Handouts
Navigable Slide Index
- Introduction
- Full depth articular cartilage structure
- Structural heterogeneity of cartilage
- Cartilage has a poor repair potential
- Lesion grades
- ACI: Autologous Chondrocyte Implantation
- Chondrocyte expansion
- Reseach on articular cartilage
- Cell division in cartilage
- Bovine MCP joint
- Progenitor isolation
- Differential adhesion assay
- Colony forming efficiency after adhesion to FN
- Integrin expression
- Expansion in culture from single colonies
- Expansion in culture: maintenance of phenotype
- Transfected developing chick wing bud
- Chondroprogenitor plasticity
- Summary
- Do stem/progenitors exist in mature tissue...
- Unilateral/unicompartmental O.A.of tibial plateau
- Human cartilage adheres to FN
- Human cartilage is clonogemic
- Mechanisms that regulate stem cells
- Notch/ligand expression
- Role of Notch1 in regulation stem cells population
- Notch cleavage and ligand binding
- Non-specific Notch inhibition abolishes clonality
- S2 inhibition by TIMP 3 inhibits CFE
- Mechanism of Notch1 activation
- Notch siRNA
- Non-specific activation by Jagged 1
- Human cartilage notch 1 expression
- Summary
- References
- References
- Acknowledgements
Topics Covered
- Cartilage repair
- Cartilage progenitor isolation and characterization
- Human articular cartilage progenitors
- The role of Delta/Notch signalling in progenitor proliferation
Talk Citation
Archer, C. (2007, October 1). Cartilage stem cells: tools for joint repair? [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 26, 2024, from https://doi.org/10.69645/DUUA8403.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Charles Archer has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Cartilage stem cells: tools for joint repair?
Published on October 1, 2007
17 min