• General Strategies in Biomarker Research
• 55 min
  1. The proteomic revolution

  • Dr. Larry Gold
• 39 min
  2. Lipid biomarkers: lipidomics of the macrophage and plasma lipidomes

  • Prof. Edward A. Dennis
• New Tools for Biomarker Research
• 38 min
  3. The future of CNVs: sequence based resolution and links to human disease 1

  • Prof. Evan Eichler
• 31 min
  4. The future of CNVs: sequence based resolution and links to human disease 2

  • Prof. Evan Eichler
• 59 min
  5. Development of glyco-biomarkers using glycoproteomics technologies

  • Dr. Hisashi Narimatsu
• 32 min
  6. Circulating nucleic acids as biomarkers in cancer patients

  • Prof. Klaus Pantel
• Specific Disease Applications
• 28 min
  7. Biomarkers in breast cancer

  • Prof. Joe Duffy
• 71 min
  8. Bacterial biomarkers

  • Dr. Christiane Honisch
• 32 min
  9. Diabetes biomarkers

  • Prof. Naveed Sattar
• 60 min
  10. Gene networks, brain networks: understanding schizophrenia

  • Dr. Daniel Weinberger
• 29 min
  11. Biomarkers for Huntington's disease - promises and challenges

  • Prof. Sarah Tabrizi
• 31 min
  12. Update on fluid biomarkers for neurodegenerative diseases

  • Prof. Henrik Zetterberg
• 31 min
  13. Biomarkers in osteoarthritis

  • Dr. Ali Mobasheri
• Biomarkers in Drug Discovery and Delivery
• 31 min
  14. Pharmacogenomics: emphasis on clinical drug development

  • Dr. Amelia Warner
• 25 min
  15. Biomarkers in drug development: potential use and challenges

  • Dr. Abdel-Bassett Halim
• 41 min
  16. Patient stratification for drug treatment in oncology and other diseases

  • Dr. Tim Harris
• Biomarkers in development, nutrition, and health
• 50 min
  17. Building genetic and environmental marker models to predict exceptional survival

  • Prof. Thomas Perls
• 29 min
  18. Ethnic differences in nutrition

  • Prof. Jose Ordovas
• 55 min
  19. Non-invasive prenatal diagnostics

  • Prof. Y. M. Dennis Lo
• 44 min
  20. Epigenetic biomarkers in cancer

  • Prof. Bob Brown
• Archived Lectures *These may not cover the latest advances in the field
• 23 min
  21. Biomarkers for Alzheimer's disease

  • Prof. Henrik Zetterberg

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Definitions
3. Major drivers for patient stratification
4. Technologies
5. Data integration is key
6. Breast cancer
7. Transcriptional profiling and breast cancer
8. Molecular profiling in NSCLC
9. FDA approves Crizotinib & companion test
10. Integration of molecular profiling into the clinic
11. Tumour sequencing for personalised oncology
12. Identification of genes affecting drug response
13. Recent advances in genetics for other diseases
14. Common alleles (MS)
15. ALS genetics
16. Future electronic health record
17. Thanks

Topics Covered

• Personalised medicine in Oncology
• Patient stratification using molecular markers
• Next generation genome sequencing and data handling
• Drivers of patient stratification including payors
• Molecular profiling in lung and breast cancer
• Relevance of these approaches for ALS, MS and other neurological diseases

Links

Series:

• Biomarkers

Categories:

• Cancer
• Clinical Practice

Therapeutic Areas:

• Oncology

Talk Citation

Publication History

• Published on September 27, 2012

Financial Disclosures

• Dr. Tim Harris, Stock Shareholder (Self-managed): Biogen Idec; Other: employee of Biogen Idec.