On Sunday, April 20th 2025, starting 8:30am GMT, there will be maintenance work that will involve the website being unavailable during parts of the day. We apologize for any inconvenience this may cause and appreciate your understanding.
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
- View the Talks
-
68 min
1. The mononuclear phagocyte system: tissue resident macrophages - activation and regulation- Prof. Emeritus Siamon Gordon
-
25 min
2. Biosimilars: when value meets cost- Prof. Fernando de Mora
-
25 min
3. Mononuclear phagocytes - origins, fates and functions- Prof. Steffen Jung
-
39 min
4. Transcription factors in macrophage differentiation- Dr. Michael Sieweke
-
44 min
5. Fetal macrophages- Prof. Paul Martin
-
44 min
6. The alveolar macrophage- Dr. Ronald G. Crystal
-
35 min
7. Airway macrophages in health and disease- Prof. Tracy Hussell
-
65 min
8. Intestinal macrophages - heterogeneity, origins and functions- Prof. Allan Mowat
-
27 min
9. Osteoclasts: what do they do and how do they do it?- Prof. Steven L. Teitelbaum
-
51 min
10. The biology of Fc receptors and complement receptors- Prof. Steven Greenberg
-
71 min
-
38 min
12. Tumour-associated macrophages- Prof. Michele De Palma
- Dr. Mario Squadrito
-
42 min
13. The recognition of pathogens by C-type lectins- Prof. Gordon D. Brown
-
34 min
14. Macrophage phagocytosis- Prof. Joel Swanson
-
30 min
15. Macrophage CD36 and atherosclerosis- Dr. Maria Febbraio
-
31 min
16. Toll-Like receptor signaling and the innate immune response- Dr. Kate Fitzgerald
-
43 min
17. Innate immune receptors as mediators of systemic inflammation and pathogenesis of malaria- Prof. Ricardo Gazzinelli
-
34 min
-
69 min
19. Triggering receptors expressed on myeloid cells (TREM)- Dr. Daniel W. McVicar
-
60 min
20. Influence of eicosanoid lipid mediators on macrophage innate immune functions- Prof. Marc Peters-Golden
-
47 min
21. Macrophage paired receptor interactions- Prof. Neil Barclay
-
45 min
22. Macrophage heterogeneity in atherosclerosis regression- Prof. Edward Fisher
-
35 min
23. Gaucher disease: from lysosomal storage to immunopathology- Prof. Johannes M.F.G. Aerts
-
26 min
24. Macrophage in asthma- Prof. Douglas Robinson
-
51 min
25. The macrophage mannose receptor- Dr. Luisa Martinez-Pomares
-
41 min
26. Myeloid-derived suppressor cells in cancer- Prof. Dmitry Gabrilovich
-
29 min
27. EGF-TM7 receptors- Dr. Jörg Hamann
- Dr. Hsi-Hsien Lin
-
37 min
28. Macrophages in helminth infection- Prof. Judith Allen
- Archived Lectures *These may not cover the latest advances in the field
-
49 min
29. Immunosuppressive mechanisms in myeloid cells- Prof. Dmitry Gabrilovich
Printable Handouts
Navigable Slide Index
- Introduction
- The role of embryonic machrophages
- Ilya Metchnikoff (1845-1916)
- Drosophila - the fruit fly
- Macrophages in a Drosophila embryo
- Migrating macrophages in wound model
- Macrophages engulfing debris
- Studying macrophage migration
- Transition to responsive macrophages
- The zebrafish model for wound healing
- Fin inflammation assay
- Fin inflammation assay - movie
- L-plastin antibody
- Macrophage extravasation (1)
- Macrophage extravasation (2)
- Embryonic / feotal macrophages in the mouse
- Programmed cell death
- Macrophages during programmed cell death
- Limb development in PU.1 knock out mice
- Mesenchymal cells can act as macrophages (1)
- Mesenchymal cells can act as macrophages (2)
- Cell death cascade and related genes
- ABC1 is required for engulfing apoptotic cells
- Key roles for macrophages in development
- References
Topics Covered
- The history of studying of macrophages
- The benefits of the various model organisms for studying macrophages; zebrafish, mice, drosophila and C. elegans
- The primary function of embryonic macrophages is to clear away apoptotic cell debris
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Martin, P. (2012, June 13). Fetal macrophages [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 19, 2025, from https://doi.org/10.69645/BAXG8858.Export Citation (RIS)
Publication History
- Published on June 13, 2012
Financial Disclosures
- Prof. Paul Martin has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
