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Navigable Slide Index

1. Introduction
2. The role of embryonic machrophages
3. Ilya Metchnikoff (1845-1916)
4. Drosophila - the fruit fly
5. Macrophages in a Drosophila embryo
6. Migrating macrophages in wound model
7. Macrophages engulfing debris
8. Studying macrophage migration
9. Transition to responsive macrophages
10. The zebrafish model for wound healing
11. Fin inflammation assay
12. Fin inflammation assay - movie
13. L-plastin antibody
14. Macrophage extravasation (1)
15. Macrophage extravasation (2)
16. Embryonic / feotal macrophages in the mouse
17. Programmed cell death
18. Macrophages during programmed cell death
19. Limb development in PU.1 knock out mice
20. Mesenchymal cells can act as macrophages (1)
21. Mesenchymal cells can act as macrophages (2)
22. Cell death cascade and related genes
23. ABC1 is required for engulfing apoptotic cells
24. Key roles for macrophages in development
25. References

Topics Covered

• The history of studying of macrophages
• The benefits of the various model organisms for studying macrophages; zebrafish, mice, drosophila and C. elegans
• The primary function of embryonic macrophages is to clear away apoptotic cell debris

Links

Series:

• Macrophage Heterogeneity and Function

Categories:

• Biochemistry
• Cell Biology
• Immunology

Therapeutic Areas:

• Gynaecology & Obstetrics
• Immunology & Inflammation

Talk Citation

Publication History

• Published on June 13, 2012

Financial Disclosures

• Prof. Paul Martin has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.