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• 25 min
  1. Mononuclear phagocytes - origins, fates and functions

  • Prof. Steffen Jung
• 39 min
  2. Transcription factors in macrophage differentiation

  • Dr. Michael Sieweke
• 44 min
  3. Fetal macrophages

  • Prof. Paul Martin
• 44 min
  4. The alveolar macrophage

  • Dr. Ronald G. Crystal
• 35 min
  5. Airway macrophages in health and disease

  • Prof. Tracy Hussell
• 65 min
  6. Intestinal macrophages - heterogeneity, origins and functions

  • Prof. Allan Mowat
• 27 min
  7. Osteoclasts: what do they do and how do they do it?

  • Prof. Steven L. Teitelbaum
• 51 min
  8. The biology of Fc receptors and complement receptors

  • Prof. Steven Greenberg
• 71 min
  9. A paradigm shift in the brain-immune relationships: infiltrating macrophages in central nervous system repair

  • Prof. Michal Schwartz
• 38 min
  10. Tumour-associated macrophages

  • Prof. Michele De Palma
  • Dr. Mario Squadrito
• 42 min
  11. The recognition of pathogens by C-type lectins

  • Prof. Gordon D. Brown
• 34 min
  12. Macrophage phagocytosis

  • Prof. Joel Swanson
• 30 min
  13. Macrophage CD36 and atherosclerosis

  • Dr. Maria Febbraio
• 31 min
  14. Toll-Like receptor signaling and the innate immune response

  • Dr. Kate Fitzgerald
• 43 min
  15. Innate immune receptors as mediators of systemic inflammation and pathogenesis of malaria

  • Prof. Ricardo Gazzinelli
• 34 min
  16. KARAP/DAP12/TYROBP: three names and a multiplicity of biological functions in cellular interactions

  • Prof. Eric Vivier
• 69 min
  17. Triggering receptors expressed on myeloid cells (TREM)

  • Dr. Daniel W. McVicar
• 60 min
  18. Influence of eicosanoid lipid mediators on macrophage innate immune functions

  • Prof. Marc Peters-Golden
• 47 min
  19. Macrophage paired receptor interactions

  • Prof. Neil Barclay
• 45 min
  20. Macrophage heterogeneity in atherosclerosis regression

  • Prof. Edward Fisher
• 35 min
  21. Gaucher disease: from lysosomal storage to immunopathology

  • Prof. Johannes M.F.G. Aerts
• 26 min
  22. Macrophage in asthma

  • Prof. Douglas Robinson
• 51 min
  23. The macrophage mannose receptor

  • Dr. Luisa Martinez-Pomares
• 41 min
  24. Myeloid-derived suppressor cells in cancer

  • Prof. Dmitry Gabrilovich
• 29 min
  25. EGF-TM7 receptors

  • Dr. Jörg Hamann
  • Dr. Hsi-Hsien Lin
• 37 min
  26. Macrophages in helminth infection

  • Prof. Judith Allen
• Archived Lectures *These may not cover the latest advances in the field
• 49 min
  27. Immunosuppressive mechanisms in myeloid cells

  • Prof. Dmitry Gabrilovich

Printable Handouts

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Navigable Slide Index

1. Introduction
2. The mononuclear phagocyte system
3. Outline of presentation
4. The hematopoietic system
5. Mononuclear phagocyte origins
6. Mouse monocyte subsets
7. Human monocyte subsets
8. Inflammatory and patrolling monocytes
9. Monocyte origins
10. Monocyte origins - mixed BM chimeras (1)
11. Monocyte origins - mixed BM chimeras (2)
12. Conclusion I: Mononuclear phagocyte origins
13. Monocyte fates
14. Conditional mononuclear phagocyte ablation
15. Monocytes reconstitute macrophages
16. MDPs, not monocytes yield splenic cDCs
17. Hierarchy of MDP, monocytes and cDCs
18. Conclusion II: Mononuclear phagocyte origins
19. Gastrointestinal tract
20. Intestinal macrophages
21. The CX(3)CR1/L1 reporter animals (1)
22. The CX(3)CR1/L1 reporter animals (2)
23. Lamina propria mononuclear phagocytes (1)
24. Lamina propria mononuclear phagocytes (2)
25. Migratory DCs and resident macrophages
26. Steady state vs. inflammation
27. Inflammation recruits a novel CX(3)CR1int subset
28. CX(3)CR1int infiltrate is monocyte-derived
29. CX(3)CR1int infiltrate requires CCR2
30. CX(3)CR1int infiltrate promotes inflammation
31. Expression analysis of monocyte progeny
32. CX(3)CR1int respond to bacterial products (1)
33. CX(3)CR1int respond to bacterial products (2)
34. Conclusion
35. Acknowledgments

Topics Covered

• Distinct development of macrophages and dendritic cells
• Distinct functions of dendritic cells and macrophages in the maintenance of gut homeostasis
• The role of inflammatory monocyte infiltrates in gut inflammation

Links

Series:

• Macrophage Heterogeneity and Function

Categories:

• Biochemistry
• Cell Biology
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on May 8, 2012

Financial Disclosures

• Prof. Steffen Jung has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.