Dendritic cells and the eye: their role in the ocular immune response

Published on May 5, 2014   51 min

Other Talks in the Series: Cells of the Innate Immune System

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This is a Henry Stewart talk, and I'm John Forrester from the University of Aberdeen, Scotland. My presentation is on dendritic cells in the eye and their role in the ocular immune response.
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Dendritic cells were discovered by Ralph Steinman in 1973. Steinman and Cohn reported this in the Journal of Experimental Medicine of a novel cell type in the peripheral lymphoid organs of mice. Later Ralph Steinman identified these as the most potent antigen presenting cells promoting the adaptive immune response. And he also later identified them, in fact, as having a major role in homeostasis of the immune response by promoting non-responsiveness to immune stimulation, i.e. tolerance. For this work he had international recognition in 2007 with the Lasker Award, and most recently has been awarded the Nobel Prize for this work.
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Dendritic cells and the eye: their role in the ocular immune response

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