a Henry Stewart talk,
and I'm John Forrester from the
University of Aberdeen, Scotland.
My presentation is on
dendritic cells in the eye
and their role in the
ocular immune response.
Dendritic cells were discovered
by Ralph Steinman in 1973.
Steinman and Cohn reported this
in the Journal of Experimental
Medicine of a novel cell type in the
peripheral lymphoid organs of mice.
Later Ralph Steinman identified
these as the most potent antigen
presenting cells promoting
the adaptive immune response.
And he also later
identified them, in fact,
as having a major role in
homeostasis of the immune response
by promoting non-responsiveness to
immune stimulation, i.e. tolerance.
For this work he had
international recognition in 2007
with the Lasker Award,
and most recently
has been awarded the
Nobel Prize for this work.