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- Clinical Introduction
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1. Frontotemporal dementia
- Prof. Bruce Miller
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2. Parkinson disease
- Prof. Stanley Fahn
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3. Atypical parkinsonian syndromes
- Dr. David Burn
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4. Huntington's disease
- Prof. Roger Barker
- Neuroimaging
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5. Molecular brain imaging (PET) in diseases with dementia
- Prof. Karl Herholz
- Pathology, Genetic and Molecular Aspects (1)
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6. A molecular understanding of Alzheimer's disease
- Prof. John Hardy
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7. Neuropathology of neurodegenerative disorders
- Prof. Jillian Kril
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9. Ubiquitination and Alzheimer related disorders
- Prof. John Mayer
- Pathology, Genetic and Molecular Aspects (2)
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10. The molecular biology of Huntington's disease
- Prof. David C. Rubinsztein
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11. Metals, oxidative stress and neurodegeneration
- Prof. Ashley Bush
- Latest Developments in the Field
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12. Animal models of tauopathy
- Prof. David Westaway
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13. Parkinson's disease and transplants
- Prof. Roger Barker
- Archived Lectures *These may not cover the latest advances in the field
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14. Neuropathology of neurodegenerative disorders
- Prof. Jillian Kril
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15. Motor neurone disease: molecular basis
- Prof. Kevin Talbot
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16. Alzheimer's disease (AD)
- Prof. John Hodges
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17. Frontotemporal dementia syndromes
- Prof. John Hodges
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18. Motor neurone disease: clinical aspects
- Prof. Kevin Talbot
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19. Neuro-imaging in dementia: using MRI in routine work-up
- Prof. Philip Scheltens
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20. Prion diseases
- Prof. Pierluigi Gambetti
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21. Mitochondrial disorders and neurodegeneration
- Prof. Anthony Schapira
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23. Mutations in parkinsonian syndromes
- Dr. Andrew Singleton
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25. Frontotemporal dementia
- Prof. Bruce Miller
Printable Handouts
Navigable Slide Index
- Intro slide
- Outline of talk
- Practice parameter - guidelines
- Practice recommendation
- Potentially reversible conditions
- Potentially reversible primary aetiologies
- The decreasing prevalence of reversible dementias
- Treatable cause (?) - 1
- Treatable cause (?) - 2
- Reason for MRI in evaluation of dementia
- "Treatable causes" with imaging
- The 'exclusionary' approach to dementia
- The 'inclusionary' approach
- Changing indications for imaging
- Basic MRI protocol
- The spectrum of FTLD
- The need to look at all slices
- Subcortical vascular cognitive impairment
- CADASIL
- Specific type of vascular dementia
- Thalamic lesions in vascular dementia
- CJD: sporadic and variant
- CBD
- PSP
- Medial temporal lobe (MTL) in AD
- Alzheimer's Disease: Braak stages
- Hippocampal volume
- The 'fingerprint' of AD
- MTL atrophy: visual rating
- Visual rating of MTA
- Visual rating of MTA - examples
- Visual rating of MTA - reliability
- Visually and volumetrically estimated MTA
- Correlation with pathology
- Assessment MTL atrophy - qualitative rating
- Volumetry of MTA
- Visual rating and volumetry of the MTL
- Diagnostic value of MTA - AD vs. ND
- Diagnostic value of MTA - AD vs. C
- MTA assessment in routine practice
- MTA on MRI in dementia with LB and VaD
- Study results
- Patterns of cerebral atrophy in dementia with LB
- MRI volumetric study of dementia with LB
- Temporal lobe on MRI in PD with dementia
- Presenile/senile difference in hippocampal atrophy
- Analysis using voxal based morphometry
- MTA in MCI
- MTA predicts AD in patients with MCI
- MTA predicts dementia in patients with MCI
- MTA visual score
- Conclusions
Topics Covered
- Changing role of structural imaging in dementia
- Current diagnostic use
- Sensitivity and specificity
- Identifying biological markers for disease
- Examples from clinical practice
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Scheltens, P. (2007, October 1). Neuro-imaging in dementia: using MRI in routine work-up [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 3, 2024, from https://doi.org/10.69645/HHYE5858.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Philip Scheltens has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.