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- Overview of Chaperone Networks
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1. Mapping the molecular chaperone interaction network in yeast
- Prof. Walid A. Houry
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2. The interaction network of the GroEL chaperonin
- Prof. Dr. F. Ulrich Hartl
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3. Human heat shock protein families
- Prof. Herman Kampinga
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4. Extracellular proteostasis: an emerging field
- Prof. Mark Wilson
- Proteasome Networks
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6. Biogenesis of the eukaryotic proteasome
- Prof. Mark Hochstrasser
- Understanding Intrinsically Disordered Proteins in Protein Homeostasis
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7. Intrinsically unstructured proteins: regulation and disease
- Dr. M. Madan Babu
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8. The roles of intrinsic disorder in protein interaction networks
- Prof. Vladimir N. Uversky
- Gene Regulatory Networks and their Role in Protein Homeostasis
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10. Structure, evolution and dynamics of gene regulatory networks
- Dr. M. Madan Babu
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12. Protein-protein interaction networks
- Prof. Peter Csermely
- Protein Homeostasis in the Endoplasmic Reticulum
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13. Role of calnexin and calreticulin in protein homeostasis within the endoplasmic reticulum
- Prof. David B. Williams
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14. The unfolded protein response
- Prof. Kazutoshi Mori
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15. Role of ER stress in cystic fibrosis airway inflammation
- Dr. Carla Maria Pedrosa Ribeiro
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16. The recognition of misfolded glycoproteins in the endoplasmic reticulum
- Dr. David Y. Thomas
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17. Chaperone systems of the endoplasmic reticulum
- Prof. Linda M. Hendershot
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18. The ERAD network
- Prof. Daniel Hebert
- Protein Homeostasis in the Mitochondria
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19. Protein homeostasis in mitochondria: AAA+ chaperones & proteases
- Dr. David A. Dougan
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21. Mitochondrial chaperonin Hsp60: locations, functions and pathology
- Prof. Francesco Cappello
- Prof. Alberto J. L. Macario
- Protein Homeostasis in the Nucleus
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22. Nuclear protein quality control degradation
- Dr. Richard G. Gardner
- Protein Homeostasis in Aging Disease
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23. Protein homeostasis during ageing: C. elegans as a model organism
- Prof. Nektarios Tavernarakis
- Protein Homeostasis in Neurodegeneration
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24. Endoplasmic reticulum stress in neurodegenerative diseases
- Prof. Claudio Soto
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25. Roles for Hsp40 molecular chaperones in protein misfolding disease
- Prof. Douglas M. Cyr
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26. Protein folding in vivo
- Prof. James Bardwell
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27. Protein degradation and defense against neurodegenerative disease 1
- Prof. Alfred Goldberg
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28. Protein degradation and defense against neurodegenerative disease 2
- Prof. Alfred Goldberg
Printable Handouts
Navigable Slide Index
- Introduction
- Cellular protein homeostasis
- Proteases and chaperones
- Plants are exposed to adverse environments
- Arabidopsis thaliana: a model flowering plant
- 26S proteasome structure
- Proteasome 20S core particle
- 19S regulatory particle structure
- 19S regulatory particle function
- Arabidopsis 26S proteasome subunits
- Arabidopsis ubiquitination pathway
- Pathways affected by Arabidopsis UPS pathway
- Arabidopsis E3 ligase gene families
- Regulation of UPS pathway in Arabidopsis
- Hsp70 family chaperones in Arabidopsis
- Hsp70 structure
- Hsp70 functional cycle
- Hsp70 functions in Arabidopsis
- Arabidopsis Hsp70 interaction network
- Hsp40/J-domain family structure
- J-domain proteins in Arabidopsis
- J-domain protein functions
- J-domain protein ARC6 in plastid division
- Function of ARC6 J-domain protein
- Arabidopsis Hsp90 isoforms
- Hsp90 structure
- Hsp90 co-chaperones
- Cytosolic Hsp90 functional cycle
- Hsp90 interacts with SGT1 and RAR1
- Interactions between HSP90, SGT1 and RAR1
- AtHsp90s interaction network
- Arabidopsis heat shock transcription factors (hstfs)
- Tissue specific expression of hstfs
- Heat shock factor interaction network
- Small heat shock proteins
- Arabidopsis small heat shock proteins
- Predicted potential sHSP interactors
- Potential Arabidopsis chaperone interactions
- Thanks
Topics Covered
- Plant cellular protein quality control systems
- Arabidopsis regulated protein degradation by the proteasome
- Plant stress resistance
- Mechanism of action of molecular chaperones
- Molecular chaperones in Arabidopsis
- Chaperone interaction networks in Arabidopsis
Talk Citation
Zhao, R. (2012, February 2). Protein homeostasis and the chaperone interaction network in Arabidopsis thaliana [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved March 21, 2025, from https://doi.org/10.69645/JNEA1781.Export Citation (RIS)
Publication History
- Published on February 2, 2012
Financial Disclosures
- Prof. Rongmin Zhao has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
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