• Epidemiology and Risk Factors
• 41 min
  1. The changing prevalence of asthma

  • Dr. Deborah Jarvis
• 29 min
  2. Recent advances in asthma genetics

  • Prof. Miriam Moffatt
• 35 min
  3. Asthma: an epidemic caused by epigenetics?

  • Prof. David Schwartz
• 30 min
  4. Role of the microbiota in asthma

  • Prof. B. Brett Finlay
• 32 min
  5. Diet and asthma

  • Prof. Lewis Smith
• 43 min
  6. Obesity and asthma

  • Prof. Anne Dixon
• 35 min
  7. Occupational asthma: management beyond the textbooks

  • Prof. Paul Cullinan
• Clinical Phenotypes
• 42 min
  8. The origins of asthma

  • Prof. Peter Sly
• 46 min
  9. Pre-school wheeze

  • Prof. Andrew Bush
• 50 min
  10. Updates on the management of difficult asthma in school-aged children

  • Prof. Andrew Bush
• 24 min
  11. Smoking asthmatics

  • Prof. Neil Thomson
• 27 min
  12. Aspirin exacerbated respiratory disease

  • Prof. Chris Corrigan
• Mechanisms of Asthma
• 48 min
  13. Advances in asthma: airway inflammation

  • Prof. William Busse
• 48 min
  14. The role of mast cells in asthma

  • Prof. Peter Bradding
• 67 min
  15. Dendritic cells in asthma

  • Prof. Bart Lambrecht
• 30 min
  16. The airway smooth muscle in asthma

  • Prof. Judith Black
• 49 min
  17. Role of virus infection in asthma 1

  • Prof. Sebastian Johnston
• 27 min
  18. Role of virus infection in asthma 2

  • Prof. Sebastian Johnston
• 51 min
  19. Severe asthma: characterisation, mechanisms & treatment

  • Prof. Fan Chung
• 46 min
  20. Steroid resistance in asthma: mechanisms and potential therapies

  • Prof. Ian Adcock
• 26 min
  21. Macrophage in asthma

  • Prof. Douglas Robinson
• Diagnosis of Asthma
• 70 min
  22. Physiology of asthma and involvement of small airways

  • Prof. Charles G. Irvin
• 27 min
  23. Induced sputum in asthma

  • Prof. Antonio Spanevello
• 61 min
  24. Advances in asthma: the role of exhaled nitric oxide in the assessment and management of asthma

  • Prof. Robin Taylor
• Therapy and Management
• 41 min
  25. Pulmonary drug delivery

  • Prof. Anthony J. Hickey
• 32 min
  26. The management of chronic asthma

  • Prof. Mark Fitzgerald
• 21 min
  27. Inhaled corticosteroids and beta2-agonists

  • Dr. Omar S. Usmani
• 20 min
  28. Management of "difficult asthma"

  • Prof. Elisabeth Bel
• 47 min
  29. Management of acute exacerbations of asthma

  • Dr. Chris Fanta
• 34 min
  30. Non-pharmacological treatments for asthma

  • Prof. Neil Thomson
• 45 min
  31. Asthma: beyond the prescription

  • Prof. Martyn Partridge
• 45 min
  32. New drugs for asthma

  • Prof. Peter Barnes
• 24 min
  33. Anti-IgE therapy for asthma

  • Dr. Andrew Menzies-Gow
• Archived Lectures *These may not cover the latest advances in the field
• 45 min
  34. New drugs for asthma

  • Prof. Peter Barnes
• 35 min
  35. Asthma phenotypes in children

  • Prof. Andrew Bush
• 40 min
  36. Steroid resistance in asthma: mechanisms and potential therapies

  • Prof. Ian Adcock
• 42 min
  37. Severe asthma in children

  • Prof. Andrew Bush

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Role of virus infection in asthma
3. Disease exacerbations
4. The common cold viruses
5. Detection methods
6. Virus infections and asthma exacerbations
7. Asthma exacerbations - etiology
8. Asthmatics and LRT illness
9. Deficient IFN-beta production in asthma
10. IFN-lambda also deficient in asthmatics
11. Type III (lambda) IFNs deficient in BAL cells
12. Th1 responses related to asthma severity
13. IL-12 deficient in asthma
14. IL-18 also deficient in asthma
15. IL-15 links innate and adaptive immunity
16. IL-15 deficient in asthmatics in vivo
17. IL-15 induction by RV deficient in BAL cells
18. IL-15 deficiency related to virus load in vivo
19. IFN-alpha induction in DCs deficient in asthma
20. Increased chest symptoms and falls in PEF
21. Airway inflammation in asthmatics
22. Symptoms in AHR related to virus load
23. Specific antiviral approaches
24. Oseltamivir
25. Non-specific antiviral approaches
26. Safety study of IFN-beta in asthma
27. The macrolide azithromycin induces IFNs
28. TELICAST study
29. Conclusions: viruses in asthma exacerbations

Topics Covered

• Role of viruses in asthma exacerbations
• Huge clinical problem unmet by current therapies
• Viruses major cause in all age groups
• Deficient anti-viral immunity in asthma
• Potential therapies; specific anti-virals and broad-spectrum approaches

Links

Series:

• Advances in Asthma

Categories:

• Clinical Practice
• Immunology
• Microbiology

Therapeutic Areas:

• Immunology & Inflammation
• Infectious Diseases
• Respiratory Diseases

Talk Citation

Publication History

• Published on December 29, 2011

Financial Disclosures

• Prof. Sebastian Johnston has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.