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Printable Handouts
Navigable Slide Index
- Introduction
- Spinal cord injury
- Treatments for spinal cord injury
- Need for suitable models
- Human spinal cord injuries (1)
- Human spinal cord injuries (2)
- Human SCI: age & sex
- Human SCI: spinal level of injury
- Human SCI: mechanisms of injury
- Experimental SCI models
- Potential sources of variance
- Weight drop devices
- Force controlled devices
- Depth of tissue penetration
- Position control: linear motors
- Linear motor based impactor
- Position controlled devices
- Consistency of initial lesions
- Primary tissue damage
- Timing of tissue loss after SCI
- Secondary tissue damage
- Secondary loss of grey matter
- Secondary loss of white matter (1)
- Secondary loss of white matter (2)
- Secondary loss of white matter (3)
- Secondary loss of oligodendrocytes (1)
- Secondary loss of oligodendrocytes (2)
- Assessing tissue sparing at lesion centre
- Assessing function: BBB score
- Assessing motor function
- Summary
- Acknowledgements
Topics Covered
- Development of neuro-protective therapies
- Need for suitable experimental models
- Low variance reproducible lesions
- Spatio-temporal pattern of grey and white matter damage
Links
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Therapeutic Areas:
Talk Citation
Habgood, M. (2011, October 27). Experimental models for assessing treatments for spinal cord injury [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 5, 2024, from https://doi.org/10.69645/ATKS8762.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Mark Habgood has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.