• View the Talks
• 52 min
  1. Traumatic brain injury: from the ball field to the battlefield

  • Prof. Alan Faden
• 29 min
  2. Avoiding missed diagnosis of mild traumatic brain injury

  • Dr. John Bedolla
• 81 min
  3. Basic mechanisms of spinal cord injury (SCI)

  • Prof. Edward D. Hall
• 38 min
  4. Neuroinflammation and spinal cord injury

  • Prof. Phillip Popovich
• 46 min
  5. Experimental models for assessing treatments for spinal cord injury

  • Dr. Mark Habgood
• 52 min
  6. Experimental approaches to developing and evaluating novel treatments for TBI and SCI

  • Prof. W. Dalton Dietrich
• 62 min
  7. The treatment of spinal cord injury: past, present and future

  • Prof. James Fawcett
• 26 min
  8. The management of the patient with an acute spinal cord injury

  • Dr. Doug Brown
• 32 min
  9. Promoting neuroplasticity for functional restoration after SCI

  • Prof. Edelle Field-Fote
• 40 min
  10. Physical rehabilitation after spinal cord injury: maximizing function

  • Prof. Jennifer Hastings
• 28 min
  11. Therapies for spinal cord injury: perspective from industry

  • Dr. Andrew Blight
• 28 min
  12. Spinal cord injury: some reflections on living with tetraplegia

  • Prof. Jonathan Cole
• 25 min
  13. Coping beyond adversity: living with a spinal cord injury

  • Mr. Gary Allsop
• 34 min
  14. Identifying the trauma footprint of acquired brain injury

  • Dr. Christine Durham
• 32 min
  15. Acquiring better insight into what it's like to have acquired brain injury

  • Dr. Christine Durham
• 25 min
  16. Molecular imaging in epilepsy

  • Prof. Matthias Koepp
• 17 min
  17. Spinal cord injury and physical activity: transforming rehabilitation

  • Prof. Mary Galea
• 44 min
  18. Rehabilitation of military related neurotrauma

  • Dr. Michael Yochelson
• 41 min
  19. Spinal cord injury in natural disasters

  • Prof. Colleen O'Connell

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Edwin Smith surgical papyrus
3. Traumatic Brain Injury (TBI)
4. Heterogeneity of traumatic brain injury
5. Concussion definition (1)
6. Concussion definition (2)
7. Mild TBI a misnomer
8. Recovery from concussion
9. Neurocognitive testing after concussion
10. Brain physiology is related to recovery
11. Post-concussion symptoms
12. Effects of repetitive sports concussion
13. Gender and recovery from mild TBI
14. Gender and more severe TBI
15. Age & recovery from TBI in high school athletes
16. Aging and TBI
17. Chronic neurodegeneration and TBI
18. Chronic neurodegeneration over time - MRI study
19. Complexity of blast effects
20. Statistics: invisible wounds of war
21. Tissue damage mechanisms caused by TBI
22. Pathways of secondary injury in TBI
23. Necrosis vs. apoptosis
24. Two forms of cell death caused by TBI
25. Complex relationships exist in brain after TBI
26. Genomics and CNS injury
27. Changes in gene expression after brain injury
28. CDK inhibitors
29. Flavopiridol effect on brain tissue after TBI (1)
30. Flavopiridol effect on brain tissue after TBI (2)
31. Flavopiridol effect on recovery
32. Gene expression change after injury
33. Microglia associated factors
34. NADPH oxidase is up-regulated following TBI
35. NADPH oxidase inhibition reduces lesion size
36. Comparison of pre-clinical & clinical studies
37. Pre-clinical evaluation design criteria
38. Laser targeted vs. multipotential treatment
39. Multipotential drugs for TBI
40. Multipotential drugs for TBI - in vitro models
41. Genomic changes affected by 35b treatment
42. Effects of treatment with a multipotential drug (1)
43. Effects of treatment with a multipotential drug (2)
44. Improving likelihood of successful clinical trials
45. Summary

Topics Covered

• Heterogeneity of traumatic brain injury
• Concussion
• Mild TBI
• Neurocognitive testing
• Brain physiology is related to recovery
• Post-concussion symptoms
• Effects of repetitive sports concussion
• Gender and recovery
• Age and recovery
• Chronic neurodegeneration
• Complexity of blast effects
• Pathways of secondary injury in TBI
• Genomics and CNS injury
• Recommended design criteria for pre-clinical evaluation of pharmacological agents for TBI
• Laser targeted strategies
• Multipotential treatment
• In vitro models
• Improving likelihood of successful clinical trials

Links

Series:

• Neurotrauma

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on October 27, 2011

Financial Disclosures

• Prof. Alan Faden has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.