• View the Talks
• 50 min
  1. Where the thoughts dwell: history of neuroscience and introduction into neuroglia

  • Prof. Alexei Verkhratsky
• 35 min
  2. Astrocytes: definition, appearance and general physiology 1

  • Prof. Alexei Verkhratsky
• 30 min
  3. Astrocytes: definition, appearance and general physiology 2

  • Prof. Alexei Verkhratsky
• 39 min
  4. Glial calcium signalling

  • Prof. Alexei Verkhratsky
• 33 min
  5. Astroglial calcium signalling: what it could tell us

  • Prof. Dmitri Rusakov
• 42 min
  6. Neuronal-glial chemical transmission mediated by glutamate and ATP

  • Prof. Alexei Verkhratsky
• 27 min
  7. Energy and amino acid neurotransmitter metabolism in astrocytes

  • Prof. Helle Waagepetersen
• 49 min
  8. Mechanisms of glutamate release from astrocytes

  • Prof. Vladimir Parpura
• 37 min
  9. Cannabinoid type 1 receptors in astrocytes

  • Prof. Giovanni Marsicano
• 34 min
  10. Neuronal-glial anatomical plasticity in the hypothalamus

  • Dr. Stéphane H.R. Oliet
• 25 min
  11. General physiology of oligodendrocytes

  • Prof. Arthur M. Butt
• 35 min
  12. Neuropathology of microglia and oligodendrocytes

  • Prof. Arthur M. Butt
• 38 min
  13. Oligodendroglia/MCT1 are an unexpected contributor to CNS toxicity/neurodegeneration

  • Prof. Jeffrey D. Rothstein
• 41 min
  14. Physiology and pathophysiology of microglia

  • Prof. Dr. Uwe-Karsten Hanisch
• 39 min
  15. Properties of regulated exocytosis in astrocytes

  • Prof. Robert Zorec
• 49 min
  16. Exocytosis and gliocrine astroglia

  • Prof. Robert Zorec
• 37 min
  17. Noradrenergic hypothesis of neurodegeneration and astroglia

  • Prof. Robert Zorec
• 45 min
  18. Principles of astrogliopathology: from reactivity to atrophy and degeneration

  • Prof. Alexei Verkhratsky
• 23 min
  19. Regulation of synaptic plasticity by astroglia

  • Prof. Dmitri Rusakov
• 48 min
  20. Enteric glia: the glue of the enteric nervous system

  • Dr. Keith A. Sharkey
• 38 min
  21. Purinergic neuron-to-glia signaling in the enteric nervous system

  • Dr. Brian D. Gulbransen
• 43 min
  22. Astrocytes and Alexander disease: the first - but not last - primary astrocyte disease

  • Prof. Albee Messing
• 45 min
  23. Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons

  • Prof. Vladimir Parpura
• 43 min
  24. The impact of astrocyte mitochondrial ATP production on neuroprotection after stroke

  • Prof. James Lechleiter
• 33 min
  25. Hepatic encephalopathy in cirrhosis: a disorder of glial-neuronal signalling

  • Prof. Roger F. Butterworth
• 33 min
  26. Hepatic encephalopathy in acute liver failure: a primary neurogliopathy

  • Prof. Roger F. Butterworth
• 37 min
  27. Bi-directional communication at the neurovascular unit: implications for neuronal function

  • Prof. Jessica A. Filosa
• 51 min
  28. Astrocyte reactivity

  • Prof. Michael Sofroniew
• 36 min
  29. Roles of microglia in the healthy brain

  • Dr. Marie-Ève Tremblay
• Archived Lectures *These may not cover the latest advances in the field
• 44 min
  30. Astroglia in neuropathology

  • Prof. Alexei Verkhratsky
• 44 min
  31. Cell biology and physiology of astroglia

  • Prof. Alexei Verkhratsky
• 29 min
  32. General physiology of oligodendrocytes and Schwann cells

  • Prof. Arthur M. Butt

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Microglia and oligodendrocytes
3. Microglia
4. Development of microglia
5. Embryonic microglia
6. Adult microglia
7. Activated microglia
8. Microglial processes monitor the environment
9. Pathological signals activate microglia
10. Roles of purine receptors in microglial activation
11. Microglia and pathogenic pain
12. Oligodendrocytes
13. Degeneration
14. Peripheral nervous system (PNS) degeneration
15. Schwann cells (SC) in PNS injury
16. Central nervous system (CNS) degeneration
17. Nogo is a major myelin inhibitory molecule
18. Myelin contains multiple axon growth inhibitors
19. Myelin proteins inhibit axon growth - mechanisms
20. Oligodendrocyte precursor cells (NG2-glia)
21. Demyelination
22. Multiple Sclerosis (MS) involves all glial cell types
23. Diverse factors involved in MS
24. Glutamate is cytotoxic for oligodendrocytes
25. Ischemic cell death in immature oligodendrocytes
26. ATP acting on P2X7 receptors in demyelination
27. MS is characterised by white matter lesions
28. Relapse remitting MS
29. Acute phase of MS
30. Active lesions in MS
31. Remyelination in MS
32. Neurodegeneration in MS
33. Chronic (inactive) MS lesions
34. Why does remyelination ultimately fail in MS?
35. Conclusions

Topics Covered

• Microglia
• Oligodendrocytes
• Degeneration
• SC in PNS injury
• CNS degeneration
• Mechanisms of axon growth inhibition by myelin proteins
• Oligodendrocyte precursor cells (NG2-glia)
• Demyelination
• Multiple sclerosis

Links

Series:

• Physiology and Pathophysiology of Neuroglia

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on July 19, 2011

Financial Disclosures

• Prof. Arthur M. Butt has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.