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• 50 min
  1. Where the thoughts dwell: history of neuroscience and introduction into neuroglia

  • Prof. Alexei Verkhratsky
• 35 min
  2. Astrocytes: definition, appearance and general physiology 1

  • Prof. Alexei Verkhratsky
• 30 min
  3. Astrocytes: definition, appearance and general physiology 2

  • Prof. Alexei Verkhratsky
• 39 min
  4. Glial calcium signalling

  • Prof. Alexei Verkhratsky
• 33 min
  5. Astroglial calcium signalling: what it could tell us

  • Prof. Dmitri Rusakov
• 42 min
  6. Neuronal-glial chemical transmission mediated by glutamate and ATP

  • Prof. Alexei Verkhratsky
• 27 min
  7. Energy and amino acid neurotransmitter metabolism in astrocytes

  • Prof. Helle Waagepetersen
• 49 min
  8. Mechanisms of glutamate release from astrocytes

  • Prof. Vladimir Parpura
• 37 min
  9. Cannabinoid type 1 receptors in astrocytes

  • Prof. Giovanni Marsicano
• 34 min
  10. Neuronal-glial anatomical plasticity in the hypothalamus

  • Dr. Stéphane H.R. Oliet
• 25 min
  11. General physiology of oligodendrocytes

  • Prof. Arthur M. Butt
• 35 min
  12. Neuropathology of microglia and oligodendrocytes

  • Prof. Arthur M. Butt
• 38 min
  13. Oligodendroglia/MCT1 are an unexpected contributor to CNS toxicity/neurodegeneration

  • Prof. Jeffrey D. Rothstein
• 41 min
  14. Physiology and pathophysiology of microglia

  • Prof. Dr. Uwe-Karsten Hanisch
• 39 min
  15. Properties of regulated exocytosis in astrocytes

  • Prof. Robert Zorec
• 49 min
  16. Exocytosis and gliocrine astroglia

  • Prof. Robert Zorec
• 37 min
  17. Noradrenergic hypothesis of neurodegeneration and astroglia

  • Prof. Robert Zorec
• 45 min
  18. Principles of astrogliopathology: from reactivity to atrophy and degeneration

  • Prof. Alexei Verkhratsky
• 23 min
  19. Regulation of synaptic plasticity by astroglia

  • Prof. Dmitri Rusakov
• 48 min
  20. Enteric glia: the glue of the enteric nervous system

  • Dr. Keith A. Sharkey
• 38 min
  21. Purinergic neuron-to-glia signaling in the enteric nervous system

  • Dr. Brian D. Gulbransen
• 43 min
  22. Astrocytes and Alexander disease: the first - but not last - primary astrocyte disease

  • Prof. Albee Messing
• 45 min
  23. Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons

  • Prof. Vladimir Parpura
• 43 min
  24. The impact of astrocyte mitochondrial ATP production on neuroprotection after stroke

  • Prof. James Lechleiter
• 33 min
  25. Hepatic encephalopathy in cirrhosis: a disorder of glial-neuronal signalling

  • Prof. Roger F. Butterworth
• 33 min
  26. Hepatic encephalopathy in acute liver failure: a primary neurogliopathy

  • Prof. Roger F. Butterworth
• 37 min
  27. Bi-directional communication at the neurovascular unit: implications for neuronal function

  • Prof. Jessica A. Filosa
• 51 min
  28. Astrocyte reactivity

  • Prof. Michael Sofroniew
• 36 min
  29. Roles of microglia in the healthy brain

  • Dr. Marie-Ève Tremblay
• Archived Lectures *These may not cover the latest advances in the field
• 44 min
  30. Astroglia in neuropathology

  • Prof. Alexei Verkhratsky
• 44 min
  31. Cell biology and physiology of astroglia

  • Prof. Alexei Verkhratsky
• 29 min
  32. General physiology of oligodendrocytes and Schwann cells

  • Prof. Arthur M. Butt

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. General introduction
3. Demyelination
4. Schwann cells (SC)
5. Non-myelinating Schwann cells
6. Terminal/Perisynaptic SC (1)
7. Terminal/Perisynaptic SC (2)
8. SC in PNS injuries and demyelination
9. Oligodendrocytes and myelinating Schwann cells
10. Schwann cells have perinodal microvilli
11. Schwann cells have a basal lamina
12. Laminin, neuregulin signalling in PNS myelination
13. Laminin, neuregulin signalling in CNS myelination
14. The myelin sheath
15. Node of Ranvier
16. Myelin sheath increases conduction speed
17. Myelin sheaths are large sheets of membrane
18. Structure of the myelin sheath
19. Role of gap junctions and potassium channels
20. Myelin composition
21. CNS myelin lipids
22. GalC and sulfatide essential for axoglial adhesion
23. Main CNS myelin proteins
24. Main PNS myelin proteins
25. Other important myelin proteins
26. Transport of myelin components
27. MBP trafficking
28. Translocation of MBP mRNA
29. Development of myelinating cells
30. Functional development of Schwann cells
31. Regulation of Schwann cell differentiation
32. Developmental origin of oligodendrocytes
33. Control of oligodendrocyte differentiation
34. Conclusions

Topics Covered

• Demyelination
• Schwann cells
• SC in PNS injuries and demyelination
• CNS dysmyelination in the absence of laminin or neuregulin signaling
• The myelin sheath
• Node of Ranvier
• Role of gap junctions and potassium channels
• Myelin proteins
• Oligodendrocytes

Links

Series:

• Physiology and Pathophysiology of Neuroglia

Categories:

• Cell Biology
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on July 13, 2011
• Archived on July 31, 2022

Financial Disclosures

• Prof. Arthur M. Butt has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.