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Printable Handouts
Navigable Slide Index
- Introduction
- Targets of modulation
- Membrane properties affecting neuronal excitability
- K channel gene families
- Ca channel gene families
- Na channels gene families
- The DHPG-induced mADP is voltage dependent
- The DHPG-induced mADP is mediated by Cav2.3
- DHPG modulates voltage-gated calcium currents
- mGluR5 activation modulates Cav2.3 in oocytes
- Modulation of calcium channels via NE receptors
- Modulation activity in the thalamus
- Thalamocortical circuitry
- Voltage-dependent modulation of firing mode
- Reticular activating system
- Control of thalamocortical spiking by ACh and NE
- Thalamocortical circuitry (2)
- Long term plasticity of intrinsic excitability
- Rapidly reversible effects of DHPG in hippocampus
- Long-lasting effects of dopamine modulation
- Activity-dependent modulation
- Learning-related neuromodulation in Hermissenda
- EPSP-spike potentiation
- Long-term increases in excitability (1)
- Long-term increases in excitability (2)
- Excitability changes over time
- Plasticity of action potential bursting (1)
- Plasticity of action potential bursting (2)
- Plasticity of action potential bursting (3)
- Plasticity of action potential bursting (4)
- Plasticity of action potential bursting (5)
- Plasticity of action potential bursting (6)
- Plasticity of action potential bursting (7)
- Local control of excitability
- Localized changes in neuronal excitability
- Backpropagating action potentials
- Modulation of backpropagating action potentials (1)
- Modulation of backpropagating action potentials (2)
- Modulation of activity-dependent backpropagation
- Local modulation of excitability
- Dendritic branches with strong/weak excitability
- Conversion of a weak branch to strong excitability
- Local modulation of excitability (2)
- Modulation of the axon initial segment by DA
- Increased calcium influx localized to the AIS
- Activity-dependent movement of the AIS
- Conclusions (1)
- Conclusions (2)
- References (1)
- References (2)
Topics Covered
- Synaptic integration and action potential firing
- Neuromodulation
- Modulation of firing by activation of GPCRs
- Modulation by other mechanisms
- Targets of modulation
- Modulation activity in the thalamus
- Long-term plasticity of intrinsic excitability
- Local control of excitability
Talk Citation
Spruston, N. (2011, April 7). Modulation of intrinsic neuronal excitability 2 [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 21, 2024, from https://doi.org/10.69645/BDLA8268.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Nelson Spruston has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Modulation of intrinsic neuronal excitability 2
Published on April 7, 2011
45 min